Pascal R.
- Country
- France
- Department
- Dermatology Department
Research Overview
- Evaluation of Upadacitinib Efficacy and Safety in Adult and Adolescent Patients with Severe Alopecia Areata: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study
- I4V-MC-JAIO: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of Baricitinib in Children from 6 Years to less than 18 Years of Age with Alopecia Areata
Data & Insights
Has run more than one trial at 8 of 103 partner sites.
Specializations
Alopecia areata
Pascal Reygagne’s clinical research includes alopecia areata in both pediatric and adult populations, with attention to severe disease and regrowth outcomes in extensive scalp hair loss.
- JAK inhibitor therapies
- Hair regrowth in severe alopecia areata
- Adolescent and pediatric dermatology
His work also extends to long-term treatment assessment in persistent autoimmune hair loss and to therapeutic options for patients with limited response to prior systemic treatment.
Atopic dermatitis
His research activity covers atopic dermatitis with a focus on moderate-to-severe disease, including patients managed with background topical therapy and those with inadequate response to prior advanced treatments.
- Biologic therapy in eczema
- Topical corticosteroid background treatment
- Refractory atopic dermatitis
The therapeutic interest centers on immune-targeted approaches for chronic inflammatory skin disease in adolescent and adult populations.
Folliculitis decalvans
Pascal Reygagne is also involved in research on folliculitis decalvans, a difficult-to-treat inflammatory scalp disorder marked by chronic follicular damage and scarring alopecia.
- Immunomodulatory targeted drugs
- Scarring alopecia
- Chronic inflammatory scalp disease
This area reflects an interest in identifying therapeutic strategies for patients with persistent disease activity and limited treatment options.
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