Pascal D. J.
- Country
- The Netherlands
- Department
- Rheumatology
Research Overview
- Non‑inferiority of methotrexate or leflunomide discontinuation versus continuation in rheumatoid arthritis patients on TNF‑inhibitor therapy
- Evaluation of a Personalized Treatment Strategy Versus Standard Care in Rheumatoid Arthritis Using Methotrexate, Golimumab, and Hydroxychloroquine Sulfate
- Chronotherapy in Rheumatoid and Psoriatic Arthritis: A Randomized Controlled Trial of Tofacitinib Extended-Release Morning vs. Evening Dosing
Data & Insights
Has run more than one trial at 6 of 19 partner sites.
Specializations
Rheumatoid Arthritis Management
This investigator specializes in the treatment and management of rheumatoid arthritis, with particular emphasis on developing tailored therapeutic approaches. Their research focuses on evaluating treatment effectiveness through disease activity assessment and patient-reported outcomes.
- Personalized Treatment Strategies
- Disease Activity Monitoring
- Autoantibody-Based Interventions
Their work includes evaluation of glucocorticoids and JAK inhibitors in treatment protocols.
Chronotherapy Research
The investigator studies the timing of medication administration in inflammatory arthritis conditions. Their research examines the impact of morning versus evening dosing on treatment outcomes and patient response.
- Medication Timing Optimization
- Extended Release Formulations
- Patient-Reported Outcomes
Special attention is given to extended-release medication formulations and their temporal effectiveness.
Psoriatic Arthritis Studies
The investigator conducts research in psoriatic arthritis treatment modalities, focusing on innovative therapeutic approaches and assessment methods according to CASPAR criteria.
- Treatment Response Assessment
- Clinical Effectiveness Measures
- Therapeutic Strategy Optimization
Their work encompasses both clinical and translational aspects of arthritis treatment.
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