Paola T.
- Country
- Italy
- Department
- Division of Internal Medicine-Hypertension, Department of Medical Sciences
Research Overview
- An Open-Label Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Donidalorsen in Pediatric Patients with Hereditary Angioedema
- Efficacy and Safety of Deucrictibant for Prophylaxis and On-demand Treatment of Angioedema Attacks in Adults with Acquired Angioedema due to C1 Inhibitor Deficiency
- Evaluation of Long-Term Safety of Oral Deucrictibant (PHA-022121) for Acute Hereditary Angioedema Attacks in C1-Inhibitor Deficient Patients
Data & Insights
Has run more than one trial at 37 of 60 partner sites.
Specializations
Hereditary Angioedema Management
The investigator specializes in the treatment of hereditary angioedema (HAE), with particular focus on developing innovative therapeutic approaches for both adult and pediatric populations.
- Type I and II HAE management
- Acute attack intervention
- Long-term treatment strategies
Primary interest lies in evaluating novel oral treatments for acute HAE attacks and their long-term safety profiles.
Pediatric Therapeutic Development
The investigator conducts specialized research in pediatric HAE treatment, focusing on developing safe and effective therapies for young patients aged 2 to 12 years.
- Child-specific treatment protocols
- Age-appropriate therapeutic approaches
- Safety evaluation in pediatric populations
Special attention is given to developing treatments suitable for different age groups within the pediatric population.
Emergency Care Innovation
Research focuses on on-demand treatment solutions for acute HAE attacks, including the management of laryngeal attacks and severe manifestations of the condition.
- Rapid-onset therapeutic solutions
- Emergency intervention protocols
- Acute attack management
The investigator emphasizes the development of quick-acting treatments for acute episodes.
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