Paola M.
- Country
- Italy
- Department
- Istituto Nazionale Tumori Regina Elena Oncologia Medica 1
Research Overview
- Phase 3 Randomized Open‑Label Study of INCB123667 Versus Investigator’s Choice Chemotherapy Combination in Platinum‑Resistant Ovarian Cancer with Cyclin E1 Overexpression
- Randomized, Double-Blind, Placebo-Controlled Phase III Study of Olaparib Maintenance Monotherapy in BRCA-Mutated Advanced Ovarian Cancer Post-Platinum Chemotherapy
- Phase III Randomized Trial of Letrozole Versus Carboplatin and Paclitaxel in Estrogen/Progesterone Receptor-Positive Low-Grade Serous Ovarian Carcinoma
Data & Insights
Has run more than one trial at 24 of 112 partner sites.
Specializations
Gynecologic Oncology
The investigator specializes in treating advanced ovarian cancer, with particular focus on patients with BRCA mutations. Their research explores targeted maintenance therapies following platinum-based treatments.
- High-risk advanced ovarian cancer management
- BRCA-mutated cancer treatments
- Post-chemotherapy maintenance strategies
Additional expertise includes low-grade serous epithelial ovarian carcinoma and hormone receptor-positive gynecologic cancers.
Breast Cancer Treatment
The investigator focuses on treating metastatic triple-negative breast cancer, particularly in cases with PD-L1 positive expression. Their work encompasses innovative combination therapy approaches.
- Triple-negative breast cancer therapies
- Immunotherapy combinations
- First-line treatment strategies
Expertise extends to targeted therapeutic approaches for aggressive breast cancer subtypes.
Endocrine Therapy
The investigator studies hormone-based treatments in gynecologic cancers, specifically focusing on estrogen/progesterone receptor positive cancers. Their work includes comparative analysis of endocrine therapy versus traditional chemotherapy approaches.
- Hormone receptor-positive cancer treatment
- Alternative therapy evaluation
- Advanced stage disease management
Special interest in hormone-sensitive gynecologic malignancies and their treatment optimization.
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