Paloma C. R.
- Country
- Spain
- Department
- Pediatric endocrinology
Research Overview
- Efficacy and Safety of Oral Ibutamoren Mesylate in Prepubertal Children with Growth Hormone Deficiency: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study
- Phase 2 Randomized Study of Vosoritide in Pediatric Patients with Turner Syndrome, SHOX Deficiency, and Noonan Syndrome Unresponsive to Somatropin
- Efficacy and Safety of Teplizumab Versus Placebo in Stage 3 Type 1 Diabetes Patients Aged 1-25: A Randomized, Double-Blind, Phase 3 Trial
Data & Insights
Has run more than one trial at 18 of 98 partner sites.
Specializations
Pediatric Endocrinology and Growth Disorders
Clinical research activity includes pediatric hormonal disorders, with interest in growth hormone deficiency, short stature, and syndromic growth conditions such as Turner syndrome, Noonan syndrome, and short stature homeobox deficiency.
- Growth hormone deficiency in children
- Idiopathic short stature
- Turner syndrome and Noonan syndrome
- Small for gestational age
The investigator is also involved in studies relevant to pediatric metabolic disease and endocrine growth regulation.
Autoimmune and Inflammatory Disease
Research interests extend to immune-mediated conditions affecting joints, skin, and connective tissue, including juvenile idiopathic arthritis, psoriatic arthritis, rheumatoid arthritis, systemic lupus erythematosus, and systemic sclerosis.
- Juvenile idiopathic arthritis
- Psoriatic arthritis and plaque psoriasis
- Rheumatoid arthritis
- Systemic lupus erythematosus
Additional activity covers inflammatory bowel disease, hidradenitis suppurativa, and other chronic immune disorders.
Cardiovascular Medicine and Metabolic Risk
Clinical trial involvement includes atherosclerotic cardiovascular disease, heart failure, atrial fibrillation, hypertension, and lipid disorders such as hypercholesterolemia, hypertriglyceridemia, and familial hypercholesterolemia.
- Atherosclerotic cardiovascular disease
- Heart failure and cardiomyopathy
- Atrial fibrillation
- Dyslipidemia and obesity
Research also includes prevention-oriented work in stroke, myocardial infarction, and broader cardiometabolic risk reduction.
Respiratory and Allergic Disorders
The investigator is engaged in studies of chronic airway and inflammatory lung disease, with emphasis on asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, and bronchiectasis.
- Asthma, including severe and uncontrolled forms
- Chronic obstructive pulmonary disease
- Idiopathic pulmonary fibrosis
- Respiratory syncytial virus infection
Allergic and upper-airway conditions such as atopic dermatitis and chronic rhinosinusitis with nasal polyps are also represented.
Pediatric Growth, Metabolic, and Rare Disease Innovation
Research activity includes rare inherited and metabolic disorders such as glycogen storage disease type Ia, phenylketonuria, ornithine transcarbamylase deficiency, and methylmalonic acidemia, alongside endocrine conditions affecting childhood development.
- Growth and pubertal disorders
- Inborn errors of metabolism
- Rare genetic syndromes
- Pediatric endocrine disease
The investigator’s trial portfolio also touches on thyroid eye disease, type 2 diabetes mellitus, and other long-term endocrine and metabolic complications.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.