Pablo V. A.
- Country
- Spain
- Department
- Neurología
Research Overview
- A phase 2b, multinational, randomized, double-blind study to investigate the efficacy and safety of redasemtide (S-005151) compared with placebo in adult participants with acute ischemic stroke
- Evaluation of Safety, Tolerability, and Efficacy of TGD001 in Acute Ischemic Stroke Patients with or without Endovascular Thrombectomy
Data & Insights
Has run more than one trial at 2 of 81 partner sites.
Specializations
Cardiovascular medicine
Clinical research activity includes acute myocardial infarction, acute coronary syndrome, coronary artery disease, atherosclerotic cardiovascular disease, heart failure, atrial fibrillation, hypertrophic cardiomyopathy, takotsubo syndrome, aortic stenosis, and spontaneous coronary artery dissection. The therapeutic scope also extends to stroke prevention, cardiovascular risk reduction, and post-procedural antithrombotic care.
- Myocardial infarction
- Heart failure
- Coronary artery disease
- Stroke prevention
Work in this area reflects an interest in therapies for ischemic heart disease, cardiac remodeling, and device-related cardiovascular management.
Neurology and neuroimmunology
Research involvement covers multiple sclerosis, autoimmune encephalitis, epilepsy, migraine, stroke, and upper limb spasticity after neurological injury. The portfolio also includes idiopathic generalized epilepsy, refractory focal onset epilepsy, and progressive inflammatory disorders of the central nervous system.
- Multiple sclerosis
- Autoimmune encephalitis
- Epilepsy
- Migraine
Therapeutic interests include immunomodulatory treatment, relapse prevention, and approaches aimed at preserving neurological function.
Oncology and hematologic malignancies
The clinical research landscape includes breast cancer, non-small cell lung cancer, small cell lung cancer, ovarian cancer, prostate cancer, colorectal cancer, pancreatic cancer, renal cell carcinoma, and gastric cancer. Hematologic interests include acute myeloid leukemia, diffuse large B-cell lymphoma, chronic lymphocytic leukemia, small lymphocytic lymphoma, and multiple myeloma.
- Breast cancer
- Lung cancer
- Ovarian cancer
- Hematologic malignancies
Therapeutic focus spans targeted therapy, immunotherapy, and treatment strategies for early-stage, locally advanced, and metastatic cancer.
Autoimmune and inflammatory disease
Active study areas include systemic lupus erythematosus, lupus nephritis, rheumatoid arthritis, psoriatic arthritis, Sjögren’s syndrome, systemic sclerosis, IgG4-related disease, and idiopathic inflammatory myopathy. Gastrointestinal immune-mediated disease is also represented through Crohn’s disease and ulcerative colitis.
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Crohn’s disease
- Sjögren’s syndrome
The therapeutic emphasis is on immune-mediated inflammation, organ protection, and control of autoimmune flare.
Infectious disease, respiratory medicine, and metabolic care
Research activity also includes HIV infection, COVID-19, pneumonia, septic shock, bacteremia, nontuberculous mycobacterial lung infection, chronic obstructive pulmonary disease, and idiopathic pulmonary fibrosis. Additional interest extends to type 2 diabetes, hypertension, gout with hyperuricemia, and Fabry disease.
- HIV infection
- Respiratory infections
- Idiopathic pulmonary fibrosis
- Metabolic disease
Therapeutic interest includes infection prevention, antimicrobial treatment, and management of chronic respiratory and metabolic disorders.
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