Pablo G. P.
- Country
- Spain
- Department
- Cardiology
Research Overview
- Phase IIb Randomized Double‑Blind Placebo‑Controlled Study of Eplontersen Plus ALXN2220 Versus Eplontersen + Placebo in Adults with Transthyretin‑Mediated Amyloid Cardiomyopathy
- An open-label, multi-center, non-randomized pivotal Phase 3 study to evaluate the efficacy and safety of [18F]florbetaben Positron Emission Tomography (PET) imaging to diagnose cardiac AL amyloidosis
- Phase 3 Randomized Double-Blind Study of Aficamten vs. Metoprolol Succinate in Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy
Data & Insights
Has run more than one trial at 191 of 361 partner sites.
Specializations
Cardiomyopathy Research
The investigator specializes in various forms of cardiomyopathy, with particular focus on hypertrophic cardiomyopathy in both obstructive and non-obstructive forms. Their research extends to evaluating innovative treatments including mavacamten, aficamten, and danicamtiv.
- Obstructive Hypertrophic Cardiomyopathy (HCM)
- Non-obstructive HCM
- Dilated Cardiomyopathy (DCM)
The research includes evaluation of cardiac structure changes and genetic aspects of cardiomyopathy.
Amyloidosis Studies
Extensive research focuses on transthyretin amyloidosis and its cardiac manifestations. The investigator studies multiple therapeutic approaches including ALXN2220, acoramidis, and eplontersen for ATTR-CM.
- Transthyretin Amyloid Cardiomyopathy
- Hereditary Transthyretin Amyloidosis
- Cardiac AL Amyloidosis
Research includes diagnostic imaging studies and novel therapeutic interventions.
Heart Failure Research
The investigator conducts research in various types of heart failure, including studies on heart failure with preserved ejection fraction (HFpEF) and reduced ejection fraction (HFrEF).
- Heart Failure with Preserved Ejection Fraction
- Heart Failure with Reduced Ejection Fraction
- Cardiovascular Clinical Events
Studies include evaluation of novel therapeutic compounds and their impact on cardiac function.
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