Øystein F.
- Country
- Norway
- Department
- Lungeavdelingen
Research Overview
- Phase III Trial of BI 764532 Plus Atezolizumab, Carboplatin, and Etoposide as First-Line Treatment for Extensive-Stage Small Cell Lung Cancer
- Phase 3 Randomized, Double-Blind Study of Belrestotug and Dostarlimab Versus Pembrolizumab in PD-L1 High Non-Small Cell Lung Cancer
- Phase 3 Randomized Study of Sacituzumab Govitecan Versus Standard of Care in Previously Treated Extensive Stage Small Cell Lung Cancer
Data & Insights
Has run more than one trial at 80 of 258 partner sites.
Specializations
Thoracic Oncology
Clinical research in lung cancer and related thoracic malignancies, including small cell lung carcinoma, non-small cell lung cancer, mesothelioma, and pulmonary neuroendocrine tumors. The therapeutic scope also includes treatment strategies for advanced solid tumors with actionable biomarkers such as KRAS G12C and EGFR alterations.
- Small cell lung cancer
- Non-small cell lung cancer
- Mesothelioma
- Progressive fibrosing interstitial lung disease
Research activity also extends to idiopathic pulmonary fibrosis, severe asthma, and other respiratory conditions managed through oncology-linked and inflammatory disease programs.
Head and Neck and Gastrointestinal Cancers
Investigator involvement covers head and neck squamous cell carcinoma, oropharyngeal cancer, cervical squamous cell carcinoma, and anal squamous cell carcinoma, alongside upper gastrointestinal and hepatobiliary malignancies such as gastric cancer, colorectal cancer, pancreatic cancer, and biliary adenocarcinoma.
- Head and neck squamous cell carcinoma
- Cervical cancer
- Colorectal cancer
- Biliary tract cancer
Therapeutic interests include immunotherapy, checkpoint inhibition, and biomarker-driven treatment in advanced solid tumors.
Hematologic Malignancies
Clinical trial activity includes a broad range of blood cancers, with emphasis on acute myeloid leukemia, acute lymphoblastic leukemia, myelodysplastic syndromes, lymphoma, and multiple myeloma. The portfolio also spans pediatric and adult hematologic disease.
- Acute myeloid leukemia
- Acute lymphoblastic leukemia
- Myelodysplastic syndromes
- Multiple myeloma
Additional focus areas include follicular lymphoma, mantle cell lymphoma, chronic lymphocytic leukemia, and neuroblastoma in hematology-oncology programs.
Melanoma, Sarcoma, and Rare Solid Tumors
Research interests extend to melanoma, soft tissue sarcoma, gastrointestinal stromal tumor, neuroendocrine carcinoma, and other uncommon solid tumors. Activity also includes thyroid carcinoma, salivary gland carcinoma, and urothelial carcinoma.
- Melanoma
- Sarcoma
- Gastrointestinal stromal tumor
- Urothelial carcinoma
The therapeutic emphasis includes advanced disease control and postoperative or adjuvant strategies in high-risk malignancies.
Neuroinflammatory and Systemic Diseases
The investigator is also involved in non-oncology clinical research spanning multiple sclerosis, myasthenia gravis, rheumatoid arthritis, Crohn's disease, IgA nephropathy, and primary sclerosing cholangitis. This includes conditions affecting the immune system, kidneys, gastrointestinal tract, and nervous system.
- Multiple sclerosis
- Myasthenia gravis
- IgA nephropathy
- Primary sclerosing cholangitis
Additional therapeutic areas include pulmonary sarcoidosis, idiopathic pulmonary fibrosis, and selected cardiovascular disease and stroke prevention studies.
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