Olga K.
- Country
- Germany
- Department
- Kinder- und Jugendkrankenhaus AUF DER BULT
Research Overview
- Pharmacokinetics, Pharmacodynamics, and Safety Evaluation of Bempedoic Acid in Pediatric Patients with Heterozygous Familial Hypercholesterolemia
- Randomized, Double-Blind, Multicenter Study Evaluating Inclisiran Versus Placebo in Pediatric Patients with Heterozygous Familial Hypercholesterolemia
- Evaluation of Raxtozinameran Vaccination in Children with Elevated Genetic Risk for Type 1 Diabetes: Impact on Islet Autoantibody Incidence
Data & Insights
Has run more than one trial at 18 of 103 partner sites.
Specializations
Type 1 Diabetes and Islet Autoimmunity
The investigator is involved in clinical research focused on early and established type 1 diabetes, with attention to preserving beta-cell function, slowing disease progression, and addressing immune-mediated pathways linked to diabetes onset.
- New-onset type 1 diabetes
- Stage 3 type 1 diabetes
- Risk for type 1 diabetes
- Endogenous insulin secretion
- Islet autoantibodies
Her work also includes therapeutic interest in immune modulation and metabolic preservation in children and adolescents at different stages of diabetes development.
Pediatric Obesity and Metabolic Weight Management
Her research landscape includes treatment strategies for obesity and overweight in children and adolescents, with a focus on sustained weight control and metabolic health.
- Adolescent obesity
- Pediatric weight maintenance
- Reduced-calorie diet
- Physical activity
- BMI management
The therapeutic scope also extends to interventions supporting long-term control of excess body weight in younger patients.
Lipid Disorders and Familial Hypercholesterolemia
The investigator is active in pediatric cardiovascular-metabolic research addressing heterozygous familial hypercholesterolemia and elevated LDL cholesterol, with emphasis on early lipid lowering in children.
- Heterozygous familial hypercholesterolemia
- LDL-C reduction
- Pediatric dyslipidemia
- Lipid metabolism
- Cardiometabolic risk
Her clinical interests include therapies aimed at improving lipid profiles in childhood to reduce long-term vascular risk.
Pediatric Endocrinology and Growth Disorders
Her work also spans broader pediatric endocrine conditions, including short stature, growth failure, and syndromic growth disorders in children and adolescents.
- Idiopathic short stature
- SHOX deficiency
- Turner syndrome
- Small for gestational age
- Growth hormone-related disorders
This area reflects a sustained therapeutic interest in endocrine care for growth and development in pediatric populations.
Neonatal and Rare Pediatric Disease Care
Her clinical trial activity includes neonatal and rare-disease settings, with interest in improving outcomes for extremely preterm infants, newborns with hypoxic-ischemic encephalopathy, and children affected by severe inherited skin disorders.
- Hypoxic-ischemic encephalopathy
- Preterm infants
- Recessive dystrophic epidermolysis bullosa
- Junctional epidermolysis bullosa
- Neonatal neuroprotection
Her research interests also include therapies relevant to respiratory stabilization and early-life neurodevelopmental protection.
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