Nikoletta R.
- Country
- Greece
- Department
- 1st Department of Respiratory Medicine
Research Overview
- Phase 2b/3 Randomized Double‑Blind Placebo‑Controlled Study Evaluating Efficacy and Safety of Lunsekimig in Adults with Inadequately Controlled Eosinophilic COPD
- Efficacy and Safety of Anakinra in Patients with Post-Acute COVID-19 Syndrome: A Double-Blind, Randomized, Placebo-Controlled Trial
- Evaluation of Emapalumab in Patients with Interferon-Gamma Driven Sepsis: A Randomized, Placebo-Controlled Trial
Data & Insights
Has run more than one trial at 28 of 147 partner sites.
Specializations
Critical Care Medicine
The investigator specializes in treating severe systemic infections, with particular focus on sepsis and its molecular endotypes. Their research explores innovative therapeutic approaches targeting interferon-gamma-driven inflammatory responses in critical illness.
- Sepsis Endotype Classification
- Immunological Biomarkers
- Targeted Antibody Therapy
Their work includes evaluation of monoclonal antibodies for specific sepsis endotypes, aiming to improve patient outcomes in critical care settings.
Post-Viral Conditions
The investigator focuses on treating post-acute COVID syndrome (PACS), investigating therapeutic interventions for persistent symptoms following COVID-19 infection. Their research examines the role of immune system activation in long-term complications.
- COVID-19 Sequelae
- Inflammatory Response Modulation
- Respiratory Symptom Management
Their expertise extends to evaluating anti-inflammatory treatments for post-viral syndromes and their impact on clinical recovery.
Immunotherapy Applications
The investigator explores targeted immunological treatments across different disease states, focusing on monoclonal antibody therapies and their application in inflammatory conditions.
- Cytokine Modulation
- Treatment Response Assessment
- Clinical Outcome Measures
Their research encompasses the development and evaluation of immunomodulatory treatments for various inflammatory conditions.
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