Nikita K.
- Country
- Portugal
- Department
- #3601:Serviço Reumatologia
Research Overview
- Phase 3 Randomized Double‑Blind Placebo‑Controlled Study of Subcutaneous Ianalumab (VAY736) Added to Standard Therapy in Systemic Lupus Erythematosus
- Phase 3 Randomized Double-blind Placebo-controlled Study of Nipocalimab in Adults with Moderate to Severe Systemic Lupus Erythematosus
- Long-term Safety and Efficacy Assessment of Ianalumab in Sjögren’s Syndrome: A Randomized, Double-blind, Two-arm NEPTUNUS Extension Study
Data & Insights
Has run more than one trial at 90 of 249 partner sites.
Specializations
Autoimmune & Rheumatic Disorders
The investigator concentrates on systemic autoimmune conditions such as systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, psoriatic arthritis, and Sjögren's syndrome, as well as neuromuscular disorders like myasthenia gravis and idiopathic inflammatory myopathies.
- Systemic Lupus Erythematosus
- Rheumatoid Arthritis
- Systemic Sclerosis
- Psoriatic Arthritis
- Sjögren's Syndrome
Research emphasizes disease‑modifying therapies and biomarker‑driven strategies.
Inflammatory Bowel Diseases
Clinical work includes adult and pediatric cohorts with ulcerative colitis and Crohn's disease, focusing on biologic optimization and mucosal healing.
- Ulcerative Colitis
- Crohn's Disease
- Pediatric IBD
- Biologic Therapies
- Endoscopic Outcomes
Integration of subcutaneous agents and patient‑reported outcome measures guides therapeutic decisions.
Oncology (Solid Tumors & Hematologic Malignancies)
The investigator participates in trials across a spectrum of cancers, including breast cancer, non‑small cell lung cancer, colorectal cancer, ovarian cancer, and acute myeloid leukemia, with an emphasis on targeted and immunotherapeutic approaches.
- Breast Cancer
- Non‑Small Cell Lung Cancer
- Colorectal Cancer
- Ovarian Cancer
- Acute Myeloid Leukemia
Focus lies on molecularly defined subpopulations and combination regimens.
Cardiovascular & Metabolic Disorders
Research activity spans acute coronary syndrome, heart failure, atrial fibrillation, and metabolic conditions such as non‑alcoholic steatohepatitis and hyperlipidemia, targeting reduction of major adverse cardiovascular events.
- Acute Coronary Syndrome
- Heart Failure
- Atrial Fibrillation
- Non‑Alcoholic Steatohepatitis
- Hyperlipidemia
Emphasis is placed on outcome‑based metrics and preventive cardiology.
Neurological & Neurodegenerative Diseases
The investigator engages in studies of neurodegenerative and neuroinflammatory disorders, including Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis, and rare ataxias such as spinocerebellar ataxia type‑3.
- Alzheimer's Disease
- Parkinson's Disease
- Multiple Sclerosis
- Amyotrophic Lateral Sclerosis
- Spinocerebellar Ataxia Type‑3
Clinical protocols incorporate disease‑specific scales and advanced imaging biomarkers.
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