Niki S.
- Country
- Greece
- Department
- Department of Haematology
Research Overview
- An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial
- Phase 1 Dose-Determining Study of EXS73565 in Patients with Relapsed or Refractory B-Cell Malignancies Including CLL, MCL, DLBCL, FL, and MZL
- Long-term Safety of Asciminib in Patients With Philadelphia Chromosome-Positive CML or ALL Continuing From Parent Studies
Data & Insights
Has run more than one trial at 57 of 186 partner sites.
Specializations
Hematologic malignancies and bone marrow disorders
Clinical research activity is centered on acute myeloid leukemia, chronic myeloid leukemia, multiple myeloma, myelofibrosis, myelodysplastic syndromes, and lymphoid malignancies, with interest in relapsed, refractory, and newly diagnosed disease settings.
- Acute myeloid leukemia
- Multiple myeloma
- Myelofibrosis
- Chronic myeloid leukemia
- Myelodysplastic syndromes
Additional involvement extends to paroxysmal nocturnal hemoglobinuria, immune thrombocytopenia, thrombotic thrombocytopenic purpura, and thalassemia, reflecting a strong therapeutic focus in hematology.
Thoracic oncology and lung cancer
The investigator is actively involved in studies of non-small cell lung cancer, including advanced, metastatic, resectable, and biomarker-defined disease, as well as small cell lung cancer.
- Non-small cell lung cancer
- Metastatic lung cancer
- KRAS G12C-mutant disease
- EGFR-mutated disease
- Small cell lung cancer
Research interests also include immunotherapy combinations and post-surgical treatment strategies in lung cancer, with attention to molecularly targeted approaches in thoracic malignancy.
Respiratory disease and airway inflammation
Clinical trial involvement covers chronic and severe inflammatory lung conditions, including chronic obstructive pulmonary disease, asthma, bronchiectasis, cystic fibrosis, idiopathic pulmonary fibrosis, and progressive pulmonary fibrosis.
- Chronic obstructive pulmonary disease
- Severe asthma
- Idiopathic pulmonary fibrosis
- Bronchiectasis
- Cystic fibrosis
There is also interest in eosinophilic inflammation, pulmonary sarcoidosis, and severe respiratory infections, supporting a broad respiratory therapeutic portfolio.
Kidney disease, complement-mediated disorders, and thrombotic microangiopathy
Research activity includes chronic kidney disease, IgA nephropathy, idiopathic immune-complex membranoproliferative glomerulonephritis, atypical hemolytic uremic syndrome, and related complement-driven renal conditions.
- IgA nephropathy
- Chronic kidney disease
- Atypical hemolytic uremic syndrome
- Paroxysmal nocturnal hemoglobinuria
- Thrombotic microangiopathy
Additional involvement spans proteinuria, dialysis-associated inflammation, and arteriovenous graft thrombosis, indicating sustained interest in renal and hematologic overlap disorders.
Cardiovascular, neurologic, and immune-mediated conditions
The investigator’s portfolio also includes atrial fibrillation, acute coronary syndrome, myocardial infarction, ischemic stroke, and transient ischemic attack, alongside selected inflammatory and autoimmune diseases.
- Atrial fibrillation
- Ischemic stroke
- Heart failure
- Systemic lupus erythematosus
- Sepsis
Further therapeutic interest extends to epilepsy, schizophrenia, and thrombosis prevention, reflecting engagement with complex multisystem disease areas.
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