Nigel K.
- Country
- The Netherlands
- Department
- Surgery
Research Overview
- Phase II/III Randomized Trial of Autologous Dendritic Cell Vaccine (MesoPher) Following FOLFIRINOX in Patients with Borderline Resectable Pancreatic Cancer
- Evaluation of Perioperative mFOLFIRINOX and Surgical Resection Versus mFOLFIRINOX Monotherapy in Oligometastatic Pancreatic Cancer: A Randomized Controlled Trial
Data & Insights
Has run more than one trial at 5 of 34 partner sites.
Specializations
Thoracic and Gastrointestinal Oncology
Nigel Kooreman is involved in clinical research on non-small cell lung cancer, small-cell lung cancer, pancreatic cancer, colorectal cancer, and gastroesophageal cancers, with a clear focus on surgical oncology and advanced solid tumours.
- Non-small cell lung cancer
- Pancreatic cancer
- Colorectal cancer
- Gastric and esophageal cancer
His trial portfolio also includes studies in cholangiocarcinoma, urothelial carcinoma, and peritoneal metastases, reflecting a broad interest in complex oncologic disease management.
Hematologic Malignancies and Cellular Therapies
His research activity extends to lymphoma, multiple myeloma, acute leukemia, and other blood and lymphatic diseases, with attention to novel treatment strategies in relapsed and refractory settings.
- Diffuse large B-cell lymphoma
- Multiple myeloma
- Acute myeloid leukemia
- CAR T-cell therapy
He is also associated with studies in mantle cell lymphoma, myelodysplastic syndrome, and stem cell transplantation, highlighting interest in advanced hematologic care.
Cardiovascular and Cardiorenal Disease
Nigel Kooreman is active in trials addressing heart failure, myocardial infarction, coronary artery disease, cardiogenic shock, and aortic stenosis, with a surgical and perioperative perspective.
- Heart failure
- Myocardial infarction
- Coronary artery disease
- Cardiovascular risk reduction
His interests also include kidney transplantation, chronic kidney disease, and cardiorenal protection, linking vascular disease with organ preservation.
Immune-Mediated and Inflammatory Disorders
His clinical research includes Crohn’s disease, ulcerative colitis, atopic dermatitis, hidradenitis suppurativa, and psoriatic disease, covering major immune-mediated inflammatory conditions.
- Crohn’s disease
- Ulcerative colitis
- Atopic dermatitis
- Hidradenitis suppurativa
He is also involved in studies of primary biliary cholangitis, primary sclerosing cholangitis, and eosinophilic esophagitis, supporting therapeutic development in inflammatory disease.
Rare, Genetic, and Neuromuscular Conditions
His research landscape includes Pompe disease, cystic fibrosis, Angelman syndrome, myelofibrosis, and systemic mastocytosis, showing engagement with rare and genetically driven disorders.
- Pompe disease
- Cystic fibrosis
- Angelman syndrome
- Systemic mastocytosis
He also contributes to trials in neuromuscular disease, pulmonary fibrosis, and autoimmune disease, adding breadth to his therapeutic interests.
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