Nienke V. O.
- Country
- The Netherlands
- Department
- Department of Pediatrics
Research Overview
Data & Insights
Has run more than one trial at 0 of 14 partner sites.
Specializations
Pediatric Inflammatory Bowel Disease
Focus on severe ulcerative colitis and Crohn’s disease in children, emphasizing disease activity assessment and therapeutic optimization.
- Biologic therapy evaluation
- Subcutaneous drug delivery
- Pharmacokinetic profiling in pediatrics
Research integrates clinical outcomes with pediatric safety considerations.
Solid Tumor Oncology
Investigates advanced non‑small cell lung cancer, colorectal cancer, breast cancer, and renal cell carcinoma across disease stages.
- Targeted molecular therapies
- Immunotherapy combination strategies
- Comprehensive molecular profiling
Emphasis on improving outcomes for metastatic disease.
Hematologic Oncology
Studies include acute myeloid leukemia, lymphoblastic leukemia, multiple myeloma, and diverse lymphomas with a focus on treatment‑resistant cases.
- Cellular immunotherapy approaches
- JAK inhibitor resistance mechanisms
- Bone marrow transplantation outcomes
Focus on therapeutic options for refractory hematologic malignancies.
Cardiovascular Disease
Research addresses atherosclerotic cardiovascular disease, heart failure, and acute myocardial infarction, targeting underlying inflammatory pathways.
- Anti‑inflammatory therapeutic agents
- Lipid‑lowering strategies
- Risk stratification using biomarkers
Integration of clinical and laboratory data to predict adverse events.
Renal & Glomerular Diseases
Covers primary IgA nephropathy, Alport syndrome, and focal segmental glomerulosclerosis, exploring novel treatment modalities.
- Proteinuria reduction therapies
- Innovative immunomodulatory agents
- Genetic‑based therapeutic interventions
Both pediatric and adult populations are included in study cohorts.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.