Niels R.
- Country
- Germany
- Department
- Onkologisches Studienzentrum
Research Overview
- Evaluation of STX-721 in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring Specific Mutations
- Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Patients With Previously Treated TROP2-Positive Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
- Phase 2, Open-Label Study in Subjects with Previously Untreated MET Amplified Locally Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Data & Insights
Has run more than one trial at 531 of 802 partner sites.
Specializations
Non-Small Cell Lung Cancer (NSCLC)
Specializes in investigating novel therapeutic approaches for advanced and metastatic NSCLC, with particular emphasis on targeted therapies and immunotherapy combinations.
- EGFR-mutated lung cancer treatments
- PD-L1 targeted immunotherapies
- MET amplification interventions
Focuses on developing treatment strategies for both early-stage and advanced disease states.
Small Cell Lung Cancer
Conducts research in limited and extensive-stage SCLC, exploring innovative therapeutic combinations and treatment approaches.
- Platinum-based combination therapies
- Novel immunotherapy applications
- Treatment strategies for relapsed disease
Evaluates both standard-of-care and experimental therapeutic approaches.
Specialized Lung Cancer Subtypes
Investigates treatments for distinct lung cancer variants including large-cell neuroendocrine carcinoma and rare molecular subtypes.
- RET fusion-positive tumors
- KRAS G12C mutations
- TTF-1 negative adenocarcinoma
Develops personalized treatment approaches based on specific genetic and molecular profiles.
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