Nicole L.
- Country
- Italy
- Department
- Neuro-oncologia
Research Overview
Data & Insights
Has run more than one trial at 0 of 17 partner sites.
Specializations
Neuro‑Oncology
The investigator concentrates on malignant disorders of the central nervous system, encompassing primary brain neoplasms and metastatic lesions.
- Glioblastoma multiforme
- Primary central nervous system lymphoma
- Brain metastases
Research integrates molecular characterization to refine therapeutic targeting.
Breast Cancer Oncology
Clinical investigations address a spectrum of breast malignancies, from hormone‑driven disease to aggressive triple‑negative phenotypes.
- Hormone receptor‑positive breast cancer
- Triple‑negative breast cancer
- HER2‑low breast cancer
Efforts focus on overcoming resistance to endocrine and targeted agents.
Hepatobiliary & Liver Disease
Projects target malignancies and metabolic disorders of the liver and biliary tree, including both oncologic and fibrotic conditions.
- Hepatocellular carcinoma
- Cholangiocarcinoma
- Non‑alcoholic steatohepatitis (NASH)
Studies explore novel systemic and locoregional therapies.
Autoimmune & Systemic Diseases
Investigations include systemic autoimmune disorders characterized by chronic inflammation and organ involvement.
- Systemic lupus erythematosus
- Systemic sclerosis
- Vasculitis
Therapeutic strategies aim to modulate immune pathways and improve organ function.
Metabolic & Cardiovascular Disorders
Research spans metabolic dysregulation and its impact on cardiovascular risk, emphasizing integrated disease management.
- Type 2 diabetes mellitus
- Atherosclerotic cardiovascular disease
- Obesity
Clinical programs evaluate interventions that address both glycemic control and vascular health.
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