Nico B.
- Country
- The Netherlands
- Department
- 528002; Paediatrics
Research Overview
Data & Insights
Has run more than one trial at 0 of 6 partner sites.
Specializations
Pediatric Oncology
The investigator focuses on solid tumors affecting children, including rare sarcomas and neuroblastoma. Research includes hematologic malignancies such as acute lymphoblastic leukemia in the pediatric population.
- Childhood leukemia
- Pediatric sarcoma
- Neuroblastoma
- Brain tumors in children
Clinical work is conducted at the Leiden University Medical Center.
Hematology & Bone Marrow Disorders
Studies target acute myeloid leukemia across adult and pediatric cohorts. Investigations also address myelodysplastic syndromes and related marrow failure conditions.
- Acute myeloid leukemia
- Myelodysplastic syndrome
- Chronic lymphocytic leukemia
- B-cell lymphomas
- Multiple myeloma
The research site provides comprehensive transplant services.
Autoimmune & Immunology
The investigator examines systemic lupus erythematosus and its renal manifestations. Work also includes myasthenia gravis subtypes and complement-mediated kidney disease.
- Lupus nephritis
- Generalized myasthenia gravis
- ANCA-associated vasculitis
- Complement 3 glomerulopathy
- Autoimmune hemolytic anemia
Efforts aim to translate immunomodulatory strategies into pediatric care.
Cardiovascular & Metabolic
Research addresses atherosclerotic cardiovascular disease in conjunction with metabolic risk factors. Projects include alpha-1 antitrypsin deficiency related liver and lung disease.
- Atrial fibrillation
- Heart failure
- Alpha-1 antitrypsin deficiency
- Hyperlipidemia
- Obesity-associated cardiovascular risk
Collaborations extend to cardiology units within the institution.
Neurology & Neurodegenerative Disorders
The investigator explores Huntington's disease and related neurodegeneration. Additional focus is on cerebral amyloid angiopathy and stroke prevention.
- Huntington's disease
- Cerebral amyloid angiopathy
- Ischemic stroke
- Traumatic brain injury
- Neuropathic pain
Neurological studies integrate advanced imaging and biomarker analysis.
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