Nedal O.
- Country
- Czechia
- Department
- NA
Research Overview
- Efficacy and Safety Evaluation of BAY 3018250 in Symptomatic Proximal Deep Vein Thrombosis: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Trial
- Evaluation of Balcinrenone and Dapagliflozin on Cardiovascular Outcomes in Heart Failure Patients with Renal Impairment: A Phase III Randomized, Double-Blind Study
- Efficacy and Safety Evaluation of Sotagliflozin in Patients with Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy
Data & Insights
Has run more than one trial at 30 of 317 partner sites.
Specializations
Cardiovascular Medicine
Clinical research activity includes heart failure, atrial fibrillation, hypertrophic cardiomyopathy, and deep vein thrombosis, with attention to cardiovascular death, stroke prevention, and symptom control in cardiac disease.
- Heart failure and acute heart failure
- Atrial fibrillation
- Hypertrophic cardiomyopathy
- Thrombotic disease
His therapeutic focus in this area aligns with modern cardiometabolic care and treatment strategies for high-risk cardiovascular conditions.
Multiple Sclerosis and Neuroimmunology
A major area of interest is multiple sclerosis, including relapsing forms, progressive disease, spasticity, and disability progression, as well as related central nervous system inflammatory disorders such as MOG antibody-associated disease.
- Relapsing multiple sclerosis
- Progressive multiple sclerosis
- Multiple sclerosis spasticity
- MOG-AD
The portfolio also includes therapies linked to brain inflammation, MRI-based disease activity, and long-term neurological treatment continuity.
Inflammatory Bowel Disease and Gastroenterology
Research involvement extends to Crohn’s disease, ulcerative colitis, and broader inflammatory bowel disease, with therapeutic interest in disease control, remission maintenance, and associated metabolic burden.
- Crohn’s disease
- Ulcerative colitis
- Clinical remission
- Obesity or overweight in IBD
Related activity also covers short bowel syndrome, reflecting engagement with complex gastrointestinal disorders requiring targeted therapy.
Metabolic and Endocrine Disorders
Clinical trial involvement includes type 1 diabetes, type 2 diabetes, hypertriglyceridemia, and severe hypertriglyceridemia, with a clear emphasis on metabolic risk reduction and glycaemic management.
- Type 1 diabetes mellitus
- Type 2 diabetes
- Hypertriglyceridemia
- Severe hypertriglyceridemia
This area also intersects with obesity and combined cardiometabolic treatment strategies.
Dermatology, Immunology, and Infectious Disease
Additional research interests include atopic dermatitis, plaque psoriasis, hidradenitis suppurativa, hypereosinophilic syndrome, and infection-focused studies such as Clostridioides difficile infection, complicated urinary tract infection, and severe community-acquired bacterial pneumonia.
- Atopic dermatitis
- Plaque psoriasis
- Hidradenitis suppurativa
- Infectious diseases
The therapeutic scope also includes immune-mediated conditions and infection prevention in patients receiving B-cell depletion therapy.
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