N.C. V. Y.
- Country
- The Netherlands
- Department
- Interne geneeskunde
Research Overview
Data & Insights
Has run more than one trial at 0 of 17 partner sites.
Specializations
Solid Tumor Oncology
Investigation of therapeutic strategies across major solid malignancies.
- advanced non‑small cell lung carcinoma
- metastatic colorectal cancer
- triple‑negative breast cancer
- rectal cancer
- her2‑positive breast cancer
Emphasis on improving survival outcomes in high‑risk disease.
Hematologic Malignancies
Focus on targeted and combination therapies for lymphoid and plasma cell disorders.
- chronic lymphocytic leukemia
- small lymphocytic lymphoma
- multiple myeloma
- venetoclax‑based regimens
- acalabrutinib combinations
Aims to achieve deep minimal residual disease responses.
Neurovascular Headache Disorders
Development of preventive and acute treatments for migraine subtypes.
- episodic migraine
- chronic migraine
- pediatric migraine management
- migraine without aura
- migraine with aura
Prioritizes long‑term safety and tolerability.
Women’s Health and Hormone‑Related Symptoms
Addressing vasomotor and endocrine therapy–related adverse effects in breast cancer survivors.
- moderate to severe vasomotor symptoms
- hot flashes
- adjuvant endocrine therapy
- CDK4/6 inhibition
- non‑steroidal aromatase inhibition
Seeks to improve quality of life during hormonal treatment.
Thrombosis Prevention in Orthopedic Surgery
Evaluation of individualized prophylactic regimens to reduce venous thromboembolism after joint replacement.
- total hip arthroplasty
- total knee arthroplasty
- risk‑adapted thrombosis prophylaxis
- bleeding safety
- symptomatic VTE incidence
Focuses on balancing efficacy and safety across risk strata.
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