Mircea P.
- Country
- France
- Department
- Psychiatrie
Research Overview
- A Long-term, Open-Label Study to Evaluate the Safety, Tolerability, and Efficacy of Azetukalner in Patients with Bipolar I or II Depression
- Etude de phase II évaluant la capacité d'un agoniste des récepteurs 5-HT4, le prucalopride (Resolor©), à accélérer l'efficacité thérapeutique d'un antidépresseur de type ISRS: preuve de concept clinique.
Data & Insights
Has run more than one trial at 1 of 21 partner sites.
Specializations
Psychiatric and Neurocognitive Disorders
Mircea Polosan’s clinical research interest is anchored in psychiatry, with involvement in studies addressing depression, bipolar depression, psychosis, tourette’s disorder, and neurocognitive disorders in older adults. The portfolio also includes work linked to pain and agitation in complex neuropsychiatric settings.
- Depression
- Ultra high risk of psychosis
- Tourette’s disorder
- Neurocognitive disorders
These interests extend to conditions at the interface of mental health and neurological impairment, including Parkinson’s disease and multiple sclerosis-related neuropsychiatric burden.
Sleep and Respiratory Medicine
Another major area of activity is sleep medicine and respiratory disease, especially obstructive sleep apnea in adults with overweight or obesity. The investigator is also involved in studies related to idiopathic hypersomnia, narcolepsy, and chronic respiratory conditions such as asthma, COPD, and interstitial lung disease.
- Obstructive sleep apnea
- Idiopathic hypersomnia
- Narcolepsy
- COPD
This research landscape includes interest in pulmonary hypertension, progressive pulmonary fibrosis, and severe inflammatory airway disease.
Oncology and Hematologic Malignancies
His clinical trial portfolio spans a broad range of oncology and hematologic malignancies, including non-small cell lung cancer, breast cancer, prostate cancer, hepatocellular carcinoma, lymphoma, acute leukemia, and myelodysplastic syndromes. The therapeutic focus also covers advanced and relapsed disease settings across solid tumors and blood cancers.
- Non-small cell lung cancer
- Diffuse large B-cell lymphoma
- Acute myeloid leukemia
- Myelodysplastic syndromes
Additional interests include multiple myeloma, melanoma, urothelial carcinoma, and gastrointestinal cancers, reflecting a strong presence in modern cancer therapeutics.
Autoimmune, Inflammatory, and Renal Diseases
The investigator is also active in autoimmune disease, inflammatory disease, and kidney disease research, with studies involving rheumatoid arthritis, systemic sclerosis, systemic lupus erythematosus, vasculitis, psoriatic arthritis, and inflammatory bowel disease. Renal interests include chronic kidney disease, IgA nephropathy, and kidney transplantation.
- Rheumatoid arthritis
- Systemic sclerosis
- IgA nephropathy
- Kidney transplantation
Related activity includes hereditary angioedema, urticaria, and chronic inflammatory lung disease, broadening the therapeutic scope across immune-mediated conditions.
Cardiovascular and Critical Care Medicine
Mircea Polosan’s research landscape includes cardiovascular disease, heart failure, atrial fibrillation, acute myocardial infarction, stroke, and hypertension. He is also involved in critical care and acute illness studies, including sepsis, pneumonia, mechanical ventilation, and trauma.
- Heart failure
- Acute myocardial infarction
- Stroke
- Sepsis
His trial activity also touches on pulmonary arterial hypertension, thromboembolism, and perioperative infection prevention.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.