Mira S.
- Country
- Bulgaria
- Department
- Clinic of endocrinology and metabolic diseases
Research Overview
- Evaluation of NNC0519-0130 Versus Semaglutide and Placebo in Chronic Kidney Disease with or without Type 2 Diabetes and Obesity: A Dose-Response Study
- Efficacy and Safety of Cagrilintide and Semaglutide in Participants with Type 2 Diabetes Inadequately Controlled on Metformin with or without SGLT2 Inhibitors
Data & Insights
Has run more than one trial at 6 of 160 partner sites.
Specializations
Multiple Sclerosis and Neuroimmunology
Clinical research interest includes relapsing multiple sclerosis, relapsing-remitting multiple sclerosis, and progressive multiple sclerosis, with attention to disease activity, relapse prevention, and magnetic resonance imaging endpoints in central nervous system disease.
- Relapsing multiple sclerosis
- Progressive multiple sclerosis
- MRI-based central nervous system assessment
Work in this area aligns with therapeutic development for inflammatory demyelinating disorders and imaging-supported evaluation of neurological disease burden.
Endocrinology, Diabetes, and Obesity
Research activity spans type 2 diabetes, obesity, and combined obesity and T2D management, with additional focus on cardiovascular-metabolic risk reduction and glycaemic control in chronic metabolic disease.
- Type 2 diabetes
- Obesity
- Cardiometabolic risk
The therapeutic landscape also includes interest in body-weight regulation and metabolic complications linked to cardiovascular disease.
Cardiovascular and Thrombotic Disease
Clinical involvement includes hypertension, established cardiovascular disease, high cardiovascular risk, and prevention of ischemic stroke after acute non-cardioembolic events or high-risk transient ischemic attack.
- Hypertension
- Ischemic stroke prevention
- High cardiovascular risk
This area reflects therapeutic interest in vascular protection, blood-pressure control, and reduction of major adverse cardiovascular outcomes.
Kidney and Hepatic Disorders
Research interests extend to chronic kidney disease with or without type 2 diabetes and chronic hepatitis delta, covering renal protection and antiviral treatment development in chronic organ disease.
- Chronic kidney disease
- Chronic hepatitis delta
- Diabetes-related kidney disease
The therapeutic scope includes conditions where metabolic and inflammatory mechanisms contribute to long-term organ injury.
Autoimmune, Hematologic, and Oncology Conditions
Additional clinical interests include Sjögren's disease, systemic lupus erythematosus, chronic lymphocytic leukemia/small lymphocytic lymphoma, and metastatic urothelial cancer, alongside supportive care in cancer cachexia and post-herpetic neuralgia.
- Sjögren's disease
- Systemic lupus erythematosus
- Chronic lymphocytic leukemia
Her research landscape also includes pediatric growth disorders such as short stature associated with small for gestational age, Turner syndrome, Noonan syndrome, and idiopathic short stature.
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