Milos B.
- Country
- Czechia
- Department
- Urologicka klinika
Research Overview
- Phase 3 Randomized, Double-blind, Placebo-controlled Study of Apalutamide and GnRH Agonist in High-risk Localized or Locally Advanced Prostate Cancer with Primary Radiation Therapy
- Phase 3 Randomized, Double-blind, Placebo-controlled Study of Apalutamide and Androgen Deprivation Therapy in High-risk Localized or Locally Advanced Prostate Cancer
- Phase 3 Randomized, Double-Blind Study of Niraparib, Abiraterone Acetate, and Prednisone in HRR Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer
Data & Insights
Has run more than one trial at 33 of 174 partner sites.
Specializations
Urologic Oncology
Clinical research activity is centred on urothelial carcinoma, bladder cancer, and broader genitourinary malignancies, with particular attention to advanced and metastatic disease settings.
- Urothelial carcinoma
- Muscle-invasive bladder cancer
- Metastatic urothelial cancer
- Renal cell carcinoma
- Prostate cancer
Therapeutic interests include immuno-oncology, targeted therapy, and treatment strategies for recurrent or unresectable urinary tract tumours.
Hematologic Malignancies
The investigator is involved in studies across B-cell lymphomas, chronic lymphocytic leukemia, multiple myeloma, and related marrow disorders.
- Chronic lymphocytic leukemia
- Diffuse large B-cell lymphoma
- Follicular lymphoma
- Multiple myeloma
- Myelodysplastic syndromes
Key therapeutic domains include antibody-based therapy, B-cell directed treatment, and approaches for relapsed or refractory blood cancers.
Transplant-Related and Immune-Mediated Conditions
Research involvement extends to graft-versus-host disease, infection prevention in immunocompromised patients, and immune dysregulation linked to hematologic therapy.
- Graft-versus-host disease
- Secondary hypogammaglobulinemia
- Recurrent infections
- Immune thrombocytopenia
- Autoimmune complications
Therapeutic focus includes supportive care, immune reconstitution, and prevention of infectious complications in patients receiving B-cell depletion therapy.
Renal and Inflammatory Disease
The investigator also contributes to clinical studies in kidney disease and inflammatory disorders, including conditions affecting renal function and chronic immune activation.
- IgA nephropathy
- Chronic kidney disease
- Alport syndrome
- Chronic inflammatory disease
- Systemic inflammation
Areas of interest include therapies aimed at preserving renal function and managing immune-mediated kidney disorders.
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