Mihaela-Liana V.
- Country
- France
- Department
- Médecine interne
Research Overview
Data & Insights
Has run more than one trial at 0 of 13 partner sites.
Specializations
Oncology – Head and Neck & Salivary Gland Tumors
Focuses on head and neck squamous cell carcinoma, salivary gland carcinomas, and related sinonasal malignancies.
- Radiotherapy combined with targeted agents
- Neoadjuvant chemotherapy protocols
- Immunotherapy‑based combination regimens
Explores strategies to enhance disease‑free survival and organ preservation.
Gastrointestinal & Hepatobiliary Oncology
Addresses metastatic pancreatic adenocarcinoma, metastatic colorectal cancer, hepatocellular carcinoma, and anal squamous cell carcinoma.
- Targeted therapies for CLDN18.2‑positive tumors
- Metronomic chemotherapy with low‑dose aspirin
- Combination of anti‑PD‑1 agents with chemotherapy
Evaluates novel agents to improve overall survival and response rates.
Hematology – Myelodysplastic Syndromes & Anemia
Concentrates on myelodysplastic syndrome with IDH1 mutation and transfusion‑independent anemia in lower‑risk disease.
- Erythropoiesis‑stimulating agent timing
- Biomarker‑guided treatment initiation
- Safety assessment of novel modulators
Seeks to delay transfusion dependence and improve hematologic outcomes.
Infectious Diseases & Critical Care
Encompasses chronic pulmonary aspergillosis, severe community‑acquired bacterial pneumonia, COVID‑19 pneumonia, and sepsis‑related hypotension.
- Adjunctive antifungal and antimicrobial strategies
- Immunomodulatory therapies for ICU patients
- Ventilator‑free and vasopressor‑free outcome measures
Targets reduction of mortality and secondary infections in critically ill populations.
Cardiovascular & Metabolic Disorders
Focuses on chronic decompensated heart failure, hepatic encephalopathy, and early gliflozin use in elderly patients.
- Prolonged anticoagulation for thromboembolism prevention
- Rifaximin therapy to delay encephalopathy decompensation
- Early gliflozin initiation in emergency settings
Investigates therapeutic approaches to stabilize cardiac and hepatic function.
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