Miguel B.
- Country
- Portugal
- Department
- Rheumatology
Research Overview
- Efficacy and Safety Evaluation of Fipaxalparant in Diffuse Cutaneous Systemic Sclerosis: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study
- Efficacy, Safety, and Tolerability of Subcutaneous Folate-Based Liposomes Encapsulating Methotrexate in Rheumatoid Arthritis Patients
- Efficacy and Safety of Subcutaneous Guselkumab in Bio-naive Patients with Active Psoriatic Arthritis Axial Disease: A Phase 4 Randomized, Double-blind, Placebo-controlled Study
Data & Insights
Has run more than one trial at 41 of 120 partner sites.
Specializations
Inflammatory and Autoimmune Diseases
Rheumatoid arthritis, psoriatic arthritis, juvenile psoriatic arthritis, and systemic sclerosis are central to the investigator’s clinical research profile, alongside broader work in immune-mediated skin and joint disease.
- Atopic dermatitis
- Hidradenitis suppurativa
- Diffuse cutaneous systemic sclerosis
Therapeutic interests also extend to JAK inhibition, interleukin-targeted therapy, and other advanced immunomodulatory approaches.
Gastroenterology and Hepatology
The investigator is involved in clinical research across chronic inflammatory bowel conditions and related digestive disorders, with emphasis on disease control and maintenance of remission.
- Crohn’s disease
- Ulcerative colitis
- Eosinophilic esophagitis
Additional therapeutic interest includes intestinal inflammation and long-term management of relapsing gastrointestinal disease.
Renal and Metabolic Disorders
Clinical activity includes kidney-focused research in IgA nephropathy, focal segmental glomerulosclerosis, and other proteinuric disorders, with attention to preserving renal function and limiting inflammatory injury.
- Chronic kidney disease
- IgA nephropathy
- Focal segmental glomerulosclerosis
The investigator also contributes to studies in type 2 diabetes, obesity, and non-alcoholic steatohepatitis, reflecting a metabolic disease interest linked to cardiometabolic risk.
Cardiovascular and Thrombotic Disease
Research involvement covers a broad spectrum of cardiovascular conditions, including heart failure syndromes, atherosclerotic risk reduction, and thromboembolic prevention.
- Heart failure
- Atrial fibrillation
- Atherosclerotic cardiovascular disease
Areas of interest also include pulmonary arterial hypertension, hypertension, and transcatheter aortic valve implantation-related antithrombotic strategies.
Neurology, Pulmonology, and Ophthalmology
The investigator’s portfolio also includes neurodegenerative and seizure disorders, respiratory disease, and retinal conditions, showing participation across several specialty domains.
- Epilepsy
- Parkinson’s disease
- Geographic atrophy
Additional therapeutic focus is seen in migraine, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, and diabetic macular edema.
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