Michiel C.
- Country
- The Netherlands
- Department
- Vascular medicine
Research Overview
- Phase III Randomized Open‑Label Non‑Inferiority Trial of NXT007 Prophylaxis versus Emicizumab in People with Hemophilia A
- Phase 1/2 Open-Label Study of BAY 2599023 (Peboctocogene Camaparvovec) in Adults with Severe Hemophilia A
- Pharmacokinetic-Guided Dosing of Emicizumab in Patients with Congenital Hemophilia A: A Non-Inferiority Study
Data & Insights
Has run more than one trial at 94 of 158 partner sites.
Specializations
Hemophilia Research
The investigator specializes in developing innovative treatments for both hemophilia A and B, with particular emphasis on gene therapy approaches. Their work encompasses the evaluation of advanced therapeutic solutions using AAV vector-based treatments for patients with severe and moderately severe forms of the condition.
- Long-term safety assessment of gene therapies
- Factor IX gene optimization
- Factor VIII gene delivery systems
Their expertise extends to monitoring clinical outcomes and assessing therapeutic efficacy in adult patients receiving novel gene therapy interventions.
Gastrointestinal Disorders
The investigator focuses on treating patients with short bowel syndrome, particularly examining the effectiveness of anticoagulation therapies in patients requiring long-term parenteral nutrition. Their research encompasses the evaluation of clinical and laboratory outcomes in this specific patient population.
- Parenteral nutrition management
- Anticoagulation therapy assessment
- Long-term clinical outcomes
Their work involves monitoring treatment responses and analyzing laboratory parameters in patients with complex nutritional needs.
Clinical Safety Studies
The investigator conducts comprehensive long-term safety evaluations of novel therapeutic approaches, with particular attention to gene therapy interventions. Their research includes monitoring patients for extended periods to assess treatment durability and safety profiles.
- Extended follow-up assessments
- Treatment response monitoring
- Safety profile documentation
Their expertise includes evaluating treatment outcomes across multiple years of patient follow-up.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.