Michele F.
- Country
- Italy
- Department
- Dipartimento di Patologia Chirurgica Medica e dell'Area Critica
Research Overview
- Randomized trial of RD03/2016 (levofloxacin/ketorolac) versus dexamethasone/levofloxacin eye drops for inflammation/infection after cataract surgery
- Randomized, Open-Label, Multicenter Study Comparing Preservative-Free Bimatoprost Ophthalmic Solution 0.1 mg/mL with Lumigan in Chronic Open-Angle Glaucoma or Ocular Hypertension
- A phase III multicenter, double-blind, randomized, placebo-controlled, parallel-group trial of the efficacy of citicoline eyedrops 2% on visual field preservation in patients with open angle glaucoma
Data & Insights
Has run more than one trial at 14 of 65 partner sites.
Specializations
Oncology
Clinical activity includes a broad range of solid tumors and hematologic malignancies, with particular involvement in colorectal cancer, gastric cancer, hepatocellular carcinoma, biliary tract cancer, and urothelial carcinoma. The investigator is also engaged in studies across breast cancer, lung cancer, ovarian cancer, and prostate cancer, as well as lymphoma and myeloma.
- Colorectal cancer
- Gastrointestinal malignancies
- Hepatobiliary cancer
- Urothelial carcinoma
- Breast and lung cancer
Research interests extend to targeted therapy, immuno-oncology, and treatment strategies for advanced and recurrent disease in gastrointestinal, genitourinary, and thoracic oncology.
Autoimmune and inflammatory disease
The investigator is involved in clinical research on systemic lupus erythematosus, Sjögren’s syndrome, IgG4-related disease, psoriatic arthritis, and hidradenitis suppurativa. Additional activity includes vasculitis, myositis, and chronic immune-mediated disorders affecting the skin, joints, and connective tissue.
- Systemic lupus erythematosus
- Sjögren’s syndrome
- IgG4-related disease
- Hidradenitis suppurativa
- Psoriatic arthritis
Therapeutic interest also covers biologic therapies and immune-modulating treatments for systemic inflammatory conditions with unmet clinical need.
Neurology and neurodegeneration
Research involvement spans epilepsy, Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis, and other neurodegenerative disorders. The investigator also contributes to studies in seizure disorders, cognitive impairment, and selected central nervous system diseases.
- Epilepsy and focal seizures
- Parkinson’s disease
- Alzheimer’s disease
- Amyotrophic lateral sclerosis
- Neurocognitive disorders
Therapeutic focus includes approaches for symptom control, disease modification, and preservation of neurological function.
Cardiometabolic and renal disease
The investigator’s clinical research landscape includes atrial fibrillation, atherosclerotic cardiovascular disease, heart failure, stroke prevention, hypertension, type 2 diabetes, obesity, and chronic kidney disease. Studies also touch on dialysis-related complications and vascular risk reduction.
- Atrial fibrillation
- Atherosclerotic cardiovascular disease
- Chronic kidney disease
- Type 2 diabetes
- Obesity
Interest is centered on antithrombotic therapy, cardiovascular event prevention, and metabolic risk management in patients with complex comorbidity.
Dermatology, respiratory, and rare disease
Additional clinical activity includes atopic dermatitis, psoriasis, glaucoma, thyroid eye disease, asthma, eosinophilic esophagitis, and primary biliary cholangitis. The investigator is also involved in studies of rare metabolic and genetic disorders, amyloidosis, and fibrotic lung disease.
- Atopic dermatitis
- Psoriasis
- Thyroid eye disease
- Asthma
- Rare metabolic and genetic disorders
Therapeutic interests span inflammatory skin disease, airway inflammation, and targeted treatment options for uncommon systemic conditions.
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