Michele D. S.
- Country
- Italy
- Department
- General Medicine I
Research Overview
Data & Insights
Has run more than one trial at 0 of 21 partner sites.
Specializations
Hematologic Malignancies
The investigator’s portfolio includes extensive work on follicular lymphoma, chronic lymphocytic leukemia, Waldenström macroglobulinemia, multiple myeloma, and diffuse large B‑cell lymphoma, covering both indolent and aggressive disease phenotypes.
- acute myeloid leukemia
- acute lymphoblastic leukemia
- myelodysplastic syndromes
- mantle cell lymphoma
- marginal zone lymphoma
These activities support therapeutic advances across targeted agents, cellular therapies, and maintenance strategies.
Solid Tumors
Focused investigations address major solid‑tumor entities such as breast cancer, non‑small cell lung cancer, renal cell carcinoma, colorectal cancer, and head and neck squamous cell carcinoma.
- ovarian cancer
- pancreatic ductal adenocarcinoma
- melanoma
- urothelial carcinoma
- lung cancer
The work emphasizes molecular profiling and novel targeted regimens.
Cardiovascular & Metabolic Disorders
Research activities encompass atherosclerotic cardiovascular disease, acute myocardial infarction, and various forms of heart failure, including both reduced and preserved ejection fraction phenotypes.
- atrial fibrillation
- pulmonary arterial hypertension
- transthyretin amyloid cardiomyopathy
- hypertriglyceridemia
- type 2 diabetes
Efforts target innovative anti‑inflammatory and metabolic pathways.
Pulmonary & Infectious Diseases
The investigator engages in studies of chronic airway conditions such as bronchiectasis, chronic obstructive pulmonary disease, and interstitial disorders like idiopathic pulmonary fibrosis.
- nontuberculous mycobacterial infection
- viral respiratory infections
- candidemia
- aspergillosis
- respiratory syncytial virus
These projects aim to improve outcomes in immunocompromised and high‑risk populations.
Autoimmune & Inflammatory Disorders
Clinical focus includes systemic autoimmune conditions such as systemic lupus erythematosus, lupus nephritis, and rheumatoid arthritis, together with organ‑specific diseases like psoriatic arthritis and ulcerative colitis.
- crohn's disease
- systemic sclerosis
- graft-versus-host disease
- bullous pemphigoid
- immune system diseases
Investigations prioritize immunomodulatory strategies and disease‑modifying therapies.
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