Michael T. C.
- Country
- Denmark
- Department
- Pediatrics
Research Overview
- Phase II Evaluation of Metronomic and Targeted Anti-Angiogenic Therapy with Bevacizumab in Pediatric Recurrent/Progressive Medulloblastoma, Ependymoma, and ATRT
- An international prospective umbrella trial for children with atypical teratoid/rhabdoid tumours (ATRT) including a randomized phase III study evaluating the non-inferiority of three courses of high-dose chemotherapy (HDCT) compared to focal radiotherapy as consolidation therapy
- Efficacy of Lithium Sulphate in Preventing Cognitive Processing Speed Impairment Post-CNS Radiotherapy in Pediatric Brain Tumor Patients
Data & Insights
Has run more than one trial at 14 of 87 partner sites.
Specializations
Pediatric Brain Tumors
The investigator specializes in treating various forms of pediatric brain malignancies, with particular focus on diffuse intrinsic pontine glioma (DIPG) and diffuse midline gliomas. Their expertise extends to managing complex cases involving H3K28M mutations and EZHIP positive tumors.
- High-risk medulloblastoma management
- Ependymoma treatment strategies
- Atypical teratoid/rhabdoid tumors
Their work encompasses comprehensive treatment approaches combining radiotherapy and innovative therapeutic agents.
Neuro-Oncology Innovation
The investigator focuses on developing advanced treatment protocols for brain tumors, including the evaluation of novel biological medicines and targeted therapies. Their research includes investigating the efficacy of treatments such as ONC201 in combination with conventional therapies.
- Molecular targeted therapies
- Combined treatment modalities
- Innovative radiation approaches
Their work incorporates various therapeutic strategies including conventional and hyperfractionated-accelerated radiotherapy.
Cognitive Protection Research
The investigator studies neuroprotective strategies, particularly focusing on preventing cognitive decline in pediatric patients receiving brain radiotherapy. Their research includes the investigation of lithium treatment as a protective agent against cognitive processing speed impairment.
- Post-radiation cognitive preservation
- Neuroprotective interventions
- Long-term outcome optimization
Their research aims to enhance treatment outcomes while preserving cognitive function in young patients.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.