Merlijn H.
- Country
- The Netherlands
- Department
- Surgery
Research Overview
Data & Insights
Has run more than one trial at 0 of 12 partner sites.
Specializations
Oncology
The investigator is engaged in therapeutic research across a broad spectrum of malignant neoplasms, emphasizing both solid tumors and hematologic cancers.
- non‑small cell lung cancer
- colorectal cancer
- breast cancer
- renal cell carcinoma
- melanoma
- hematologic malignancies
- gastrointestinal stromal tumor
- ovarian cancer
Research efforts target disease progression, molecular subtypes, and novel therapeutic combinations.
Cardiovascular & Metabolic Medicine
Focus is placed on disorders of the heart, vasculature, and metabolic regulation, including high‑risk patient populations.
- acute coronary syndrome
- heart failure
- atherosclerotic cardiovascular disease
- hypertension
- hyperlipidemia
- obesity
- pulmonary arterial hypertension
- venous thromboembolism
Therapeutic strategies explore risk reduction, disease‑modifying agents, and precision‑medicine approaches.
Gastroenterology & Inflammatory Bowel Disease
Investigations address chronic intestinal inflammation and related gastrointestinal disorders.
- ulcerative colitis
- Crohn’s disease
- primary sclerosing cholangitis
- celiac disease
- gastroesophageal reflux disease
- colitis ulcerative
- intestinal fistulas
Clinical work emphasizes biologic therapy, mucosal healing, and quality‑of‑life outcomes.
Nephrology & Renal Disorders
Research includes immune‑mediated and structural kidney diseases, with an emphasis on proteinuric conditions.
- primary biliary cholangitis
- focal segmental glomerulosclerosis
- IgA nephropathy
- Alport syndrome
- chronic kidney disease
- renal transplant
- nephrotic syndrome
Efforts target disease progression, renal protection, and targeted immunomodulation.
Genetic & Rare Disorders
The investigator contributes to therapeutic development for inherited and ultra‑rare conditions.
- Duchenne muscular dystrophy
- facioscapulohumeral muscular dystrophy
- retinitis pigmentosa
- spinocerebellar ataxia
- primary immunodeficiency diseases
- hereditary hemochromatosis
- Alport syndrome
Studies explore gene‑based therapies, disease‑modifying agents, and multidisciplinary care pathways.
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