Mercedes D. L.
- Country
- Spain
- Department
- Stroke Unit
Research Overview
- Efficacy and Safety of Statin Continuation vs. Discontinuation in Patients with Spontaneous Lobar Intracerebral Hemorrhage: A Randomized Controlled Trial
- Evaluation of Early Rhythm-Control Therapy with Dronedarone Hydrochloride in Combination with Antiarrhythmic Agents for Acute Ischemic Stroke and Atrial Fibrillation
Data & Insights
Has run more than one trial at 4 of 58 partner sites.
Specializations
Stroke and Cerebrovascular Disease
Clinical research activity is centered on acute and secondary prevention in ischemic stroke, including patients with atrial fibrillation, high-risk transient ischemic attack, and post-reperfusion care.
- Acute ischemic stroke
- Transient ischemic attack
- Mechanical thrombectomy
- Intracranial hemorrhage
- Stroke prevention
Interest also extends to antithrombotic strategies and neurovascular protection in patients at elevated cerebrovascular risk.
Cardiovascular Medicine
Research involvement includes coronary artery disease, myocardial infarction, acute coronary syndrome, and structural heart disease, with attention to event prevention and post-procedural outcomes.
- Coronary artery disease
- Myocardial infarction
- Transcatheter aortic valve implantation
- Spontaneous coronary artery dissection
- Takotsubo syndrome
Additional work addresses atherosclerotic cardiovascular disease, lipid lowering, and reduction of major adverse cardiovascular events.
Headache and Migraine Disorders
The investigator is actively involved in therapeutic studies for migraine, covering both acute treatment and prevention across adult and pediatric populations.
- Chronic migraine
- Episodic migraine
- Medication overuse headache
- Menstrual migraine
- Pediatric migraine
Research interests also include refractory headache syndromes and newer preventive approaches for migraine management.
Neurology and Epilepsy
Clinical trial activity covers focal epilepsy, generalized tonic-clonic seizures, and broader seizure-control strategies in patients requiring long-term neurological care.
- Focal-onset seizures
- Primary generalized tonic-clonic seizures
- Refractory epilepsy
- Idiopathic generalized epilepsy
- Seizure prevention
There is also involvement in multiple sclerosis, reflecting a wider neurological therapeutic focus beyond epilepsy.
Metabolic, Hepatic, and Inflammatory Disease
Research interests include non-alcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis, chronic hepatitis B, and acute pancreatitis, with a strong emphasis on chronic disease modification.
- NASH
- Alcohol-related liver disease
- Chronic hepatitis B
- Acute pancreatitis
- Obesity
Work in this area also includes type 2 diabetes and diabetic macular edema, linking metabolic disease with organ-specific complications.
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