Maximilien G.
- Country
- France
- Department
- Intensive Care Unit
Research Overview
- Comparison of Early versus Delayed Etoposide Initiation Strategies in Critically Ill Patients with Severe Sporadic Hemophagocytic Lymphohistiocytosis: A Randomized Trial
- Efficacy of Iloprost for the Management of Vaso-Occlusive Crises in Adults with Sickle Cell Disease: A Randomized, Double-Blind, Placebo-Controlled Study
- A Phase 2a, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety of Anumigilimab in Adults with Sickle Cell Disease
Data & Insights
Has run more than one trial at 25 of 56 partner sites.
Specializations
Autoimmune and Inflammatory Disease
Clinical research activity includes ANCA-associated vasculitis, giant cell arteritis, rheumatoid arthritis, systemic sclerosis, psoriatic arthritis, and Crohn’s disease, alongside broader work in immune-mediated skin and mucosal disorders.
- ANCA vasculitis
- Rheumatoid arthritis
- Crohn’s disease
- Systemic sclerosis
- Psoriatic arthritis
Therapeutic interests also extend to mucous membrane pemphigoid, bullous pemphigoid, cutaneous lupus erythematosus, hidradenitis suppurativa, and atopic dermatitis.
Cardiovascular and Thrombotic Disorders
Research involvement spans atrial fibrillation, heart failure, atherosclerotic cardiovascular disease, acute coronary syndrome, ischemic stroke, and venous thromboembolism, with attention to both prevention and event reduction.
- Atrial fibrillation
- Heart failure
- Ischemic stroke
- Venous thromboembolism
- Atherosclerotic cardiovascular disease
Additional areas include pulmonary embolism, pulmonary hypertension, cardiogenic shock, and post-cardiac arrest shock.
Renal Medicine and Transplantation
Clinical trial activity covers chronic kidney disease, end-stage renal disease, kidney transplantation, renal allograft rejection, and kidney transplant infection, reflecting a strong focus on renal preservation and transplant-related care.
- Chronic kidney disease
- End-stage renal disease
- Kidney transplantation
- Renal allograft rejection
- Hemolytic uremic syndrome
Interest also includes atypical hemolytic uremic syndrome, idiopathic nephrotic syndrome, lupus nephritis, and gout in patients with advanced kidney disease.
Pulmonary and Critical Care Conditions
Research spans asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, progressive pulmonary fibrosis, interstitial lung disease, and pulmonary arterial hypertension, with additional work in respiratory failure and severe infection.
- Asthma
- Idiopathic pulmonary fibrosis
- Interstitial lung disease
- Pulmonary arterial hypertension
- Chronic pulmonary aspergillosis
Other active domains include severe influenza infection, acute chest syndrome, and respiratory complications in intensive care.
Oncology and Hematologic Malignancies
Investigations include non-small cell lung cancer, melanoma, colorectal cancer, gastric cancer, urothelial cancer, and hepatocellular carcinoma, with a broad interest in solid tumor management and therapeutic innovation.
- Non-small cell lung cancer
- Melanoma
- Colorectal cancer
- Gastric cancer
- Urothelial cancer
Hematologic work also includes acute lymphoblastic leukemia, acute myeloid leukemia, lymphoma, and sickle cell disease.
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