maxime S.
- Country
- France
- Department
- Médecine Interne
Research Overview
- A multicenter randomized trial to evaluate the efficacy of pioglitazone to promote renal tolerance in ANCA-associated vasculitis - RENATO
- Phase II Study Evaluating the Efficacy and Safety of Secukinumab versus Combination Therapy in Patients with Active Severe Takayasu Arteritis
- PREP-ANCA: Randomized Trial of Pre‑emptive Rituximab Versus Clinic‑Biological Surveillance for ANCA Re‑positivation in GPA and MPA Patients in Remission
Data & Insights
Has run more than one trial at 65 of 162 partner sites.
Specializations
Cardiovascular medicine
Clinical research activity includes atherosclerotic cardiovascular disease, acute coronary syndrome, myocardial infarction, heart failure, atrial fibrillation, cardiogenic shock, stroke, venous thromboembolism, pulmonary embolism, and transthyretin amyloidosis with cardiomyopathy.
- Cardiovascular risk reduction
- Heart failure
- Thromboembolic disease
- Cardiac rhythm disorders
Research also extends to calcific aortic valve stenosis, hypertrophic cardiomyopathy, vasoplegic syndrome, and prevention of recurrent vascular events in high-risk patients.
Onco-hematology
The investigator is involved in trials across acute lymphoblastic leukemia, acute myeloid leukemia, diffuse large B-cell lymphoma, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, multiple myeloma, Hodgkin lymphoma, and peripheral T-cell lymphoma.
- Leukemia
- Lymphoma
- Plasma cell disorders
- Richter syndrome
Additional interests include mature B-cell malignancies, primary central nervous system lymphoma, plasma cell leukemia, and relapsed or refractory hematologic cancers.
Gastroenterology and hepatology
Research spans colorectal cancer, colon carcinoma, rectal cancer, biliary tract cancer, hepatocellular carcinoma, pancreatic adenocarcinoma, neuroendocrine tumors, Crohn’s disease, ulcerative colitis, and primary sclerosing cholangitis.
- Digestive oncology
- Inflammatory bowel disease
- Hepatobiliary disease
- Pancreatic cancer
The clinical portfolio also includes gastric cancer, esophageal squamous cell carcinoma, and metastatic gastrointestinal malignancies.
Autoimmune and inflammatory diseases
Therapeutic interests include giant cell arteritis, polymyalgia rheumatica, ANCA-associated vasculitis, systemic sclerosis, dermatomyositis, IgG4-related disease, immune thrombocytopenia, autoimmune hemolytic anemia, and pemphigus.
- Systemic vasculitis
- Connective tissue disease
- Immune cytopenias
- Inflammatory skin disease
Research activity also covers sarcoidosis, lupus, Sjögren’s syndrome, hidradenitis suppurativa, and psoriasis.
Respiratory, infectious, and intensive care medicine
Clinical studies address septic shock, sepsis, ventilator-associated pneumonia, community-acquired bacterial pneumonia, chronic pulmonary aspergillosis, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, pulmonary hypertension, and COVID-19.
- Critical care
- Severe respiratory infection
- Chronic lung disease
- Invasive fungal infection
Research also includes acute respiratory failure, intensive care, respiratory syncytial virus infection, and Clostridioides difficile infection.
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