Maurizio E.
- Country
- Italy
- Department
- #17006: UOC di Neurologia e Neurofisiopatologia per l’età evolutiva
Research Overview
- Phase 3 Randomized, Double‑Blind, Placebo‑Controlled Study of Oral Fenfluramine Hydrochloride in Participants with Rett Syndrome
- Evaluation of the Efficacy and Safety of Extended-Release Levetiracetam as Adjunctive Therapy in Refractory Partial Onset Epilepsy: A Randomized, Double-Blind Study
- Randomized, Double-Blinded, Vehicle-Controlled, Crossover Phase 2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intranasal Cenegermin (Recombinant Human Nerve Growth Factor [rhNGF]) in Pediatric Participants with Spastic Cerebral Palsy (CP).
Data & Insights
Has run more than one trial at 9 of 73 partner sites.
Specializations
Epilepsy and Seizure Disorders
Clinical research activity includes drug-resistant focal onset seizures and refractory partial onset epilepsy, with attention to treatment options aimed at improving seizure control in neurological conditions of childhood and adolescence.
- Focal onset seizures
- Levetiracetam
- Refractory epilepsy
The investigator’s work in this area is linked to pediatric neurology and neurophysiology, with a focus on therapeutic strategies for seizure reduction.
Rett Syndrome
Research involvement extends to Rett syndrome, a neurodevelopmental disorder associated with severe communication, motor, and cognitive impairment, with therapeutic interest in symptom management and functional improvement.
- Neurodevelopmental disorders
- Behavioural symptoms
- Cognitive impairment
This area reflects a clinical focus on interventions relevant to complex pediatric neurological disease.
Down Syndrome and Adaptive Behaviour
Clinical trial activity also includes treatment of behavioural and cognitive impairments in Down syndrome, with emphasis on adaptive functioning and daily-life skills in affected individuals.
- Adaptive behaviours
- Cognitive disability
- Developmental disorders
The therapeutic domain centers on neurodevelopmental care in children and adolescents with intellectual and behavioural challenges.
Pediatric Neurology
The investigator is affiliated with a pediatric neurology and neurophysiology unit, indicating sustained engagement with neurological disorders of development and early life.
- Childhood neurological disease
- Neurophysiological assessment
- Neurodevelopmental care
Clinical interests are concentrated in conditions where neurological dysfunction affects cognition, behaviour, and seizure control.
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