Maurice P.
- Country
- France
- Department
- Medical Oncology
Research Overview
- Dose-Escalation Study of Zongertinib in Patients with Advanced Non-Small Cell Lung Cancer and Solid Tumors with HER2 Aberrations
- Phase 3 Randomized Study of Nivolumab and Ipilimumab with Chemoradiotherapy in Locally Advanced Non-Small Cell Lung Cancer
- A Randomized Phase 3 Study of Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab, with or without Platinum Chemotherapy, in Subjects with No Prior Therapy for Advanced or Metastatic PD-L1 TPS<50% Non-squamous Non-small Cell Lung Cancer without Actionable Genomic Alterations (TROPION-Lung07)
Data & Insights
Has run more than one trial at 320 of 558 partner sites.
Specializations
Thoracic Oncology
The investigator is active in clinical research on non-small cell lung cancer, small cell lung cancer, and other advanced thoracic malignancies, with interest in biomarker-defined disease and treatment-resistant settings.
- EGFR-mutated NSCLC
- ALK-, ROS1-, and RET-altered lung cancer
- Small cell lung cancer
- Mesothelioma
Research activity also extends to advanced lung cancer populations with HER2 alterations, KRAS G12C mutations, and immune checkpoint inhibitor-based treatment strategies.
Breast and Gynecologic Oncology
Clinical trials include a strong focus on breast cancer across early, locally advanced, and metastatic disease, together with major involvement in ovarian cancer, endometrial cancer, and related gynecologic malignancies.
- HR-positive, HER2-negative breast cancer
- Triple-negative breast cancer
- Ovarian cancer
- Endometrial cancer
Additional interest is seen in HER2-positive and HER2-low breast cancer, cervical cancer, and gastrointestinal and gynecologic tumor combinations with molecular selection.
Sarcoma and Rare Solid Tumors
The investigator is engaged in studies of soft tissue sarcoma, bone sarcoma, and other rare solid tumors, including histologies with limited treatment options and molecularly selected subgroups.
- Undifferentiated pleomorphic sarcoma
- Liposarcoma
- Ewing sarcoma
- Gastrointestinal stromal tumor
Work also covers conventional chondrosarcoma, synovial sarcoma, and tenosynovial giant cell tumor, reflecting a broad therapeutic interest in rare mesenchymal cancers.
Genitourinary and Prostate Cancer
Clinical research activity includes prostate cancer, urothelial carcinoma, and renal cell carcinoma, with attention to advanced, metastatic, and biomarker-driven disease.
- Metastatic castration-resistant prostate cancer
- Urothelial carcinoma
- Renal cell carcinoma
- Muscle-invasive bladder cancer
Research interests also include PSMA-positive prostate cancer, FGFR-altered urothelial cancer, and adjuvant kidney cancer settings.
Hematologic Malignancies and Translational Oncology
The investigator participates in trials across acute leukemia, lymphoma, and other hematologic malignancies, alongside studies using molecularly targeted approaches in advanced cancer.
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Diffuse large B-cell lymphoma
- Multiple myeloma
Additional involvement includes chronic lymphocytic leukemia, myelodysplastic syndrome, and molecularly selected solid tumors with actionable alterations such as FGFR, HER2, and MTAP.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.