Maura F.
- Country
- Italy
- Department
- Dipartimento di Onco-Ematologia
Research Overview
- Phase 3 Multicenter Study of Ravulizumab Plus Best Supportive Care in Pediatric Patients with HSCT-Associated Thrombotic Microangiopathy
- Evaluation of PTC:VS-TC for Refractory Viral Infections Post-Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric and Young Adult Patients
- Open label dose-escalation and dose-expansion study to evaluate the safety, expansion, persistence and clinical activity of UCART22 (allogeneic engineered T-cells expressing Anti-CD22 Chimeric Antigen Receptor) in patients with relapsed or refractory CD22+ B-cell Acute Lymphoblastic Leukemia (B-ALL)
Data & Insights
Has run more than one trial at 38 of 95 partner sites.
Specializations
Transplant Medicine
This clinical investigator specializes in hematopoietic stem cell transplantation (HSCT) and its associated complications, with particular emphasis on pediatric patients from 1 month to 18 years of age.
- Post-transplant complications management
- Pediatric transplant medicine
- Thrombotic microangiopathy treatment
The investigator works with novel therapeutic approaches including ravulizumab in combination with best supportive care for transplant-related complications.
Viral Immunology
The investigator focuses on treating viral infections in immunocompromised patients, particularly those occurring after allogeneic stem cell transplantation.
- Virus-specific T lymphocyte therapy
- Treatment of resistant viral infections
- Family donor-derived cellular therapies
Their work encompasses the treatment of various viral infections including Adenovirus, Epstein-Barr virus, Cytomegalovirus, and BK virus.
Immunotherapy
The investigator develops advanced cellular therapy approaches for patients with compromised immune systems, focusing on personalized treatment solutions.
- In vitro T cell selection
- Adoptive cell therapy
- Treatment of refractory infections
Their research extends to both primary and secondary severe immunodeficiency conditions in young patients up to 30 years of age.
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