Matthias D.
- Country
- Germany
- Department
- Klinik für Kinder- und Jugendmedizin, pädiatrische Hämatologie und Onkologie
Research Overview
- International Euro Ewing (iEuroEwing) trial for treatment optimisation in patients with Ewing sarcoma
- International cooperative prospective study for children and adolescents with standard risk ALK-positive anaplastic large cell lymphoma (ALCL) estimating the efficacy of Vinblastine
- Evaluation of Melphalan-Based Chemotherapy Regimens in Low and Intermediate Risk Neuroblastoma: A Multicenter, Prospective Study
Data & Insights
Has run more than one trial at 227 of 323 partner sites.
Specializations
Hematologic Malignancies
The investigator specializes in treating acute lymphoblastic leukemia and mature B-cell lymphomas in pediatric and adolescent populations.
- Philadelphia chromosome-positive ALL treatment strategies
- Lymphoblastic lymphoma management
- B-cell lymphoma and leukemia therapies
Research focuses on innovative treatment approaches including immunotherapy and targeted molecular therapies.
Solid Tumors
Primary expertise in treating rhabdomyosarcoma, Ewing sarcoma, and germ cell tumors with particular focus on treatment optimization.
- Extracranial malignant germ cell tumors
- Pediatric sarcomas
- Neuroblastoma management
Implements multimodal treatment approaches combining chemotherapy, surgery, and radiation therapy.
Neuro-Oncology
Focuses on treating complex brain tumors including medulloblastoma and ependymoma in children and young adults.
- High-risk medulloblastoma treatment
- Intracranial ependymoma management
- CNS tumor radiation protocols
Develops personalized treatment strategies based on molecular profiling and risk stratification.
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