Mathieu A.
- Country
- France
- Department
- 6007: Neurologie
Research Overview
- Efficacy and Safety of NIO752 in Participants with Progressive Supranuclear Palsy Richardson Syndrome: A Phase III Randomized, Placebo-Controlled Study
- Randomized, Double‑Blind, Placebo‑Controlled Phase 3 Trial of Oral Votoplam in Adults with Huntington’s Disease Assessing cUHDRS Progression
- Efficacy of Fampridine in Spinocerebellar Ataxia SCA27B with FGF14 Gene GAA Expansion: A Randomized, Double-Blind, Placebo-Controlled Trial
Data & Insights
Has run more than one trial at 22 of 101 partner sites.
Specializations
Neurology and Demyelinating Disorders
Clinical research activity includes multiple sclerosis, acute demyelinating syndromes, myelin oligodendrocyte glycoprotein antibody-associated disease, chronic inflammatory demyelinating polyneuropathy, and other peripheral neuropathies.
- Relapsing-remitting multiple sclerosis
- Secondary progressive multiple sclerosis
- Anti-MOG antibody-associated disease
- Chronic inflammatory demyelinating polyneuropathy
- Peripheral neuropathy
The investigator is also involved in studies addressing neuropathic autoimmune disease, spasticity, seizure disorders, and movement disorders.
Autoimmune and Systemic Inflammatory Diseases
Research interests extend to rheumatoid arthritis, systemic lupus erythematosus, lupus nephritis, Sjögren’s syndrome, systemic sclerosis, and vasculitis.
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Sjögren’s syndrome
- Systemic sclerosis
- ANCA-associated vasculitis
Additional therapeutic focus includes idiopathic inflammatory myopathies, polymyositis, dermatomyositis, and polymyalgia rheumatica.
Oncology and Hematologic Malignancies
The oncology portfolio covers non-small cell lung cancer, renal cell carcinoma, urothelial carcinoma, hepatocellular carcinoma, and several lymphoid and myeloid malignancies.
- Non-small cell lung cancer
- Renal cell carcinoma
- Acute myeloid leukemia
- Diffuse large B-cell lymphoma
- Multiple myeloma
Work also includes ovarian cancer, prostate cancer, soft-tissue sarcoma, neuroblastoma, and pediatric solid tumors.
Respiratory, Critical Care, and Infectious Diseases
Clinical interests encompass severe asthma, pulmonary fibrosis, pulmonary arterial hypertension, chronic pulmonary aspergillosis, and bronchiectasis.
- Severe asthma
- Interstitial lung disease
- Pulmonary arterial hypertension
- Chronic pulmonary aspergillosis
- Sepsis
Research also spans intensive care, ventilator-associated pneumonia, severe influenza infection, and COVID-19.
Renal, Cardiovascular, and Transplant Medicine
Additional areas of interest include chronic kidney disease, acute kidney injury, kidney transplantation, heart failure, and atherosclerotic cardiovascular disease.
- Chronic kidney disease
- Acute kidney injury
- Kidney transplantation
- Heart failure
- Atherosclerotic cardiovascular disease
His research landscape also includes thromboembolic disease, hypertension, cardiogenic shock, and post-transplant complications.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.