Martine C. S.
- Country
- France
- Department
- Rheumatology
Research Overview
Data & Insights
Has run more than one trial at 0 of 7 partner sites.
Specializations
Inflammatory Joint Disorders
Investigation of chronic arthritides that drive synovial inflammation and progressive joint damage.
- Rheumatoid arthritis
- Axial spondyloarthritis
- Psoriatic arthritis
- Ankylosing spondylitis
Efforts emphasize biomarker validation and biologic pathway modulation to improve functional outcomes.
Systemic Autoimmune Connective‑Tissue Diseases
Study of multisystem autoimmune conditions that affect skin, kidneys, lungs, and musculoskeletal tissue.
- Systemic lupus erythematosus
- Lupus nephritis
- Primary Sjögren's syndrome
- Systemic sclerosis
- Idiopathic inflammatory myopathies
Research targets organ‑specific manifestations and the interplay of autoantibodies with disease activity.
Vasculitis and Small‑Vessel Inflammation
Focus on immune‑mediated vascular disorders that can involve the kidneys, lungs, and peripheral nerves.
- ANCA‑associated vasculitis
- Cryoglobulinemic vasculitis
- Behçet's disease
- Polyarteritis nodosa
Projects explore pathogenic pathways, disease severity scoring, and novel therapeutic targets.
Hereditary and Acquired Amyloidosis
Evaluation of transthyretin‑related amyloid deposition affecting nerves and the heart.
- Hereditary transthyretin amyloidosis with polyneuropathy
- Transthyretin amyloid cardiomyopathy
- Peripheral neuropathy of amyloid origin
Studies aim to delineate genotype‑phenotype correlations and assess disease‑modifying agents.
Interstitial Lung and Renal Complications of Autoimmune Disease
Investigation of pulmonary and renal sequelae that arise secondary to systemic autoimmunity.
- Interstitial lung disease associated with systemic sclerosis
- Autoimmune‑related renal impairment
- Pulmonary hypertension secondary to connective‑tissue disease
Research integrates imaging, functional testing, and immunologic profiling to improve prognostication.
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