Martha N. K.
- Country
- Austria
- Department
- Department of Neurology, Medical University Innsbruck,
Research Overview
- Phase III Evaluation of Lomustine and Temozolomide Versus Temozolomide in MGMT Promoter Methylated Glioblastoma with or without Tumor Treating Fields
- A Global, Multicenter, Prospective, Controlled, Open-Label Pivotal Study of Iodofalan (131I) Solution for Injection (TLX101-Tx) Plus Lomustine Versus Lomustine Alone in Patients with Radiographically Confirmed Recurrent Glioblastoma at First Recurrence (IPAX-3)
Data & Insights
Has run more than one trial at 2 of 38 partner sites.
Specializations
Neurology and Neurodegenerative Disorders
Clinical research activity includes Parkinson’s disease, multiple sclerosis, multiple system atrophy, Friedreich’s ataxia, Huntington’s disease, progressive supranuclear palsy, Alzheimer’s disease, and mild cognitive impairment, alongside broader work in nervous system diseases.
- Parkinson’s disease
- Multiple sclerosis
- Huntington’s disease
- Alzheimer’s disease
Interest also extends to focal-onset seizures, primary generalized tonic-clonic seizures, restless leg syndrome, narcolepsy, and delayed sleep-wake phase disorder.
Autoimmune, Inflammatory, and Rheumatologic Diseases
Research involvement covers Crohn’s disease, ulcerative colitis, sjögren’s syndrome, systemic sclerosis, systemic lupus erythematosus, cutaneous lupus erythematosus, and giant cell arteritis, reflecting a strong therapeutic focus in immune-mediated disease.
- Crohn’s disease
- Ulcerative colitis
- Sjögren’s syndrome
- Systemic sclerosis
Additional interests include hidradenitis suppurativa, vitiligo, atopic dermatitis, myasthenia gravis, and ANCA-associated vasculitis.
Cardiovascular, Thrombotic, and Metabolic Medicine
Clinical trial activity spans atherosclerotic cardiovascular disease, acute coronary syndrome, atrial fibrillation, stroke prevention, peripheral arterial disease, hypertension, and calcific aortic valve stenosis.
- Atherosclerotic cardiovascular disease
- Atrial fibrillation
- Acute coronary syndrome
- Stroke prevention
Therapeutic interests also include obesity, homozygous familial hypercholesterolemia, transthyretin amyloid cardiomyopathy, and pulmonary arterial hypertension.
Oncology and Hematologic Malignancies
The investigator is involved in studies across breast cancer, non-small cell lung cancer, ovarian cancer, lymphoma, multiple myeloma, acute leukemia, and melanoma, with activity extending to both solid and hematologic cancers.
- Breast cancer
- Non-small cell lung cancer
- Multiple myeloma
- Lymphoma
Further areas include endometrial cancer, prostate cancer, urothelial carcinoma, glioblastoma, and medulloblastoma.
Renal, Transplant, and Rare Disease Research
Research activity includes kidney transplantation, delayed graft function, autosomal dominant polycystic kidney disease, IgA nephropathy, C3 glomerulopathy, and alpha-1 antitrypsin deficiency-associated liver disease.
- Kidney transplantation
- Autosomal dominant polycystic kidney disease
- IgA nephropathy
- C3 glomerulopathy
Additional interests cover haemophilia A, severe anti-GBM antibody disease, amyloid cardiomyopathy, and rare CNS tumors.
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