Marjan W. B.
- Country
- The Netherlands
- Department
- infectious diseases
Research Overview
- Rifampicin Combination Therapy versus Targeted Antimicrobial Monotherapy in the Oral Antimicrobial Treatment Phase of Staphylococcal Prosthetic Joint Infection
- Phase II Multicenter Randomized Double-Blind Study on Phage Therapy Efficacy and Safety in Staphylococcus aureus-Induced Prosthetic Joint Infections
Data & Insights
Has run more than one trial at 1 of 30 partner sites.
Specializations
Orthopedic Infections
The investigator specializes in treating prosthetic joint infections (PJI), with particular emphasis on infections affecting hip and knee replacements. Their research encompasses innovative therapeutic approaches for managing Staphylococcus aureus infections in prosthetic joints.
- Joint Replacement Complications
- Bacterial Infection Management
- Surgical Site Infections
A key focus lies in evaluating various antimicrobial strategies including monotherapy approaches and novel therapies.
Antimicrobial Therapeutics
The investigator explores advanced treatment options including phage therapy and targeted antibiotic approaches. Their work involves studying clindamycin monotherapy and traditional combination treatments using rifampicin and fluoroquinolones.
- Alternative Therapeutic Strategies
- Antibiotic Optimization
- Treatment Efficacy Assessment
Research activities focus on comparing conventional and innovative therapeutic approaches for orthopedic infections.
Surgical Interventions
The investigator studies surgical management strategies, particularly DAIR (Debridement, Antibiotics, and Implant Retention) procedures. Their research evaluates the effectiveness of combining surgical interventions with various antimicrobial treatments.
- Implant Retention Techniques
- Surgical Outcomes
- Treatment Protocols
The work encompasses assessment of surgical intervention efficacy in prosthetic joint infections.
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