Marinela P.
- Country
- Bulgaria
- Department
- N/A
Research Overview
- Evaluation of Long-Term Safety, Tolerability, and Efficacy of Subcutaneous Amlitelimab in Patients with Moderate to Severe Atopic Dermatitis from Previous Trials
- Efficacy and Safety of Barzolvolimab in Chronic Inducible Urticaria: A Phase 2 Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study
- A multicenter, randomized, participant- and investigator -blinded, placebo-controlled, phase 2a study to assess the efficacy, safety and tolerability of GIA632 in adult participants with moderate to severe atopic dermatitis
Data & Insights
Has run more than one trial at 14 of 151 partner sites.
Specializations
Cardiovascular medicine and thrombosis prevention
Clinical research activity includes atherosclerotic cardiovascular disease, atrial fibrillation, heart failure, hypertension, and lipid disorders, with interest in reducing stroke, myocardial infarction, and other major cardiovascular events.
- Cardiovascular risk reduction
- Anticoagulation and stroke prevention
- Lipid-lowering therapy
- Heart failure with preserved or mildly reduced ejection fraction
Research involvement also extends to systemic inflammation in cardiovascular disease and to therapies targeting elevated lipoprotein(a) and residual cardiometabolic risk.
Inflammatory and autoimmune disease
The investigator is engaged in trials across rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis, juvenile idiopathic arthritis, and Crohn's disease, reflecting a strong focus on immune-mediated disorders.
- Rheumatoid arthritis
- Spondyloarthritis spectrum disorders
- Inflammatory bowel disease
- Targeted immunomodulation
Additional interest includes ulcerative colitis and therapies aimed at controlling chronic inflammatory activity in long-standing autoimmune conditions.
Dermatology and allergic disease
Research spans atopic dermatitis, chronic spontaneous urticaria, chronic inducible urticaria, prurigo nodularis, psoriasis, and vitiligo, together with upper-airway allergic conditions such as allergic rhinitis and chronic rhinosinusitis with nasal polyps.
- Inflammatory skin disease
- Urticaria and pruritic disorders
- Pigmentary disease
- Airway allergy and nasal polyposis
The therapeutic landscape also includes allergen immunotherapy and symptom-focused treatment approaches for persistent itch, rash, and nasal obstruction.
Pulmonary, infectious, and oncology interests
Clinical activity includes chronic obstructive pulmonary disease, uncontrolled asthma, respiratory viral prevention, and non-small cell lung cancer, indicating involvement across obstructive airway disease, infection prevention, and cancer care.
- COPD and asthma
- Influenza, RSV, and human metapneumovirus
- Non-small cell lung cancer
- Respiratory symptom control
Interest also covers therapies intended to improve lung function, reduce exacerbations, and support prevention of respiratory infections in older adults.
Metabolic, hepatic, and bone health
Research involvement includes type 2 diabetes, obesity, nonalcoholic fatty liver disease, metabolic dysfunction-associated steatohepatitis, hypertriglyceridemia, and osteoporosis, showing a broad interest in chronic metabolic and degenerative conditions.
- Diabetes and obesity
- Fatty liver disease and steatohepatitis
- Severe hypertriglyceridemia
- Postmenopausal osteoporosis
Additional work touches on gout with hyperuricemia and therapies addressing liver fibrosis, skeletal fragility, and metabolic inflammation.
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