Marina A.
- Country
- Italy
- Department
- SC Pediatria-Gastroenterologia, Epatologia e Fibrosi Cistica
Research Overview
- Efficacy, Safety, and Pharmacokinetics of Etrasimod in Pediatric Participants with Moderately to Severely Active Ulcerative Colitis: A Phase 2 Study
- Evaluation of Vedolizumab Intravenous as Maintenance Therapy in Pediatric Patients with Moderately to Severely Active Ulcerative Colitis
- Evaluation of Upadacitinib Efficacy, Safety, and Pharmacokinetics in Pediatric Patients with Moderate to Severe Crohn's Disease: A Phase 3 Multicenter Study
Data & Insights
Has run more than one trial at 19 of 78 partner sites.
Specializations
Gastroenterology and Inflammatory Bowel Disease
Clinical activity is centered on Crohn’s disease, ulcerative colitis, and related intestinal inflammatory disorders, with additional involvement in pouchitis, bowel urgency, and other chronic digestive conditions.
- Crohn’s disease
- Ulcerative colitis
- Active chronic pouchitis
- Bowel urgency
Research interests also extend to eosinophilic esophagitis, coeliac disease, and broader digestive system diseases relevant to pediatric gastroenterology.
Hepatology and Metabolic Liver Disease
The investigator is involved in studies of non-alcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis, cirrhosis, and hepatic encephalopathy, reflecting a strong therapeutic focus on chronic liver disease.
- Non-alcoholic steatohepatitis
- Metabolic dysfunction-associated steatohepatitis
- Cirrhosis
- Hepatic encephalopathy
Additional interest includes primary biliary cholangitis, primary sclerosing cholangitis, and alcohol-related liver disease.
Pediatric and Neonatal Medicine
Work in this area includes preterm infants, bronchopulmonary dysplasia, and pediatric digestive and respiratory complications, aligning with care for vulnerable early-life populations.
- Preterm infants
- Bronchopulmonary dysplasia
- Intestinal malabsorption
- Recurrent lower respiratory tract infections
Clinical interest also includes cystic fibrosis and pediatric kidney disease with proteinuria.
Autoimmune and Immune-Mediated Disorders
The investigator contributes to research in juvenile idiopathic arthritis, systemic lupus erythematosus, lupus nephritis, and systemic sclerosis, with emphasis on complex inflammatory and autoimmune disease management.
- Juvenile idiopathic arthritis
- Systemic lupus erythematosus
- Lupus nephritis
- Systemic sclerosis
Further involvement includes hidradenitis suppurativa, atopic dermatitis, bullous pemphigoid, and immune thrombocytopenia.
Rare Disease and Translational Therapeutics
Research activity also spans IgA nephropathy, cystic fibrosis, haemophilia, and amyloidosis, alongside selected cardiometabolic and neurologic conditions.
- IgA nephropathy
- Haemophilia
- Amyloidosis
- Cardiovascular disease
Areas of interest include thyroid eye disease, diabetic retinopathy, and Alzheimer’s disease.
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