Marie-Pierre G.
- Country
- France
- Department
- Hôpital Dupuytren - Service d'hématologie clinique et thérapie cellulaire
Research Overview
- Evaluation of Luspatercept and Epoetin Alfa in Low-Risk Myelodysplastic Syndromes Without Ring Sideroblasts Post-Erythropoiesis-Stimulating Agent Failure
- Evaluation of ASTX727 and Donor Lymphocyte Infusions Post-Allogeneic Stem Cell Transplantation in High-Risk Myelodysplastic Syndromes or Acute Myeloid Leukemia
- Phase 3 Randomized, Double-blind, Placebo-controlled Study of Tamibarotene and Azacitidine in RARA-positive Higher-risk Myelodysplastic Syndrome
Data & Insights
Has run more than one trial at 73 of 207 partner sites.
Specializations
Haematology and Cell Therapy
At Hôpital Dupuytren in Limoges, this investigator is closely involved in clinical research centred on acute leukaemias, myelodysplastic syndromes, and myeloproliferative neoplasms, with a strong emphasis on advanced haematologic malignancies and transplant-related care.
- Acute lymphoblastic leukaemia
- Acute myeloid leukaemia
- Myelodysplastic syndromes
- Allogeneic stem cell transplantation
Research activity also extends to lymphoma, multiple myeloma, and haematologic relapse, reflecting a therapeutic focus on difficult-to-treat blood cancers and post-transplant management.
Breast, Lung, and Gastrointestinal oncology
The clinical trial portfolio includes a broad range of solid tumours, especially breast cancer, non-small cell lung cancer, and gastrointestinal cancers, with interest in both locally advanced and metastatic disease.
- HER2-negative breast cancer
- Triple-negative breast cancer
- Non-small cell lung cancer
- Colorectal and pancreatic cancer
Therapeutic involvement also covers biliary tract cancer, ovarian cancer, and endometrial cancer, with attention to targeted and immuno-oncology strategies in solid-tumour care.
Autoimmune and inflammatory diseases
This investigator is engaged in studies addressing giant cell arteritis, polymyalgia rheumatica, rheumatoid arthritis, and systemic sclerosis, alongside other immune-mediated disorders requiring long-term therapeutic control.
- Giant cell arteritis
- Polymyalgia rheumatica
- Systemic sclerosis
- Inflammatory arthritis
Additional interest includes multiple sclerosis, myasthenia gravis, and vasculitis, highlighting work across chronic autoimmune conditions with neurological and systemic involvement.
Transplantation, infection, and supportive care
Clinical research also includes kidney transplantation, renal allograft rejection prevention, and infectious complications in vulnerable patients, particularly in the context of intensive haematology and transplant care.
- Kidney transplantation
- Renal allograft rejection
- Sepsis
- Pneumonia
Interest further extends to invasive fungal disease, viral infections, and thromboprophylaxis, supporting therapeutic development in complex inpatient and immunocompromised settings.
Neurology, rare disease, and metabolic liver disease
The investigator’s research landscape includes selected programmes in amyotrophic lateral sclerosis, Parkinson’s disease, and Alzheimer’s disease, as well as rare neurological and systemic disorders.
- Amyotrophic lateral sclerosis
- Parkinson’s disease
- Alzheimer’s disease
- Rare immune-mediated disorders
Additional therapeutic interests include metabolic dysfunction-associated steatohepatitis, chronic kidney disease, and amyloidosis, broadening the profile across multisystem disease areas with unmet clinical need.
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