Marie-Laure R. S.
- Country
- France
- Department
- Hôpital Amboise Paré - Endocrinologie, Diabétologie, Nutrition
Research Overview
Data & Insights
Has run more than one trial at 0 of 10 partner sites.
Specializations
Metabolic & Endocrine Disorders
The investigator focuses on disorders of glucose regulation such as type 2 diabetes, body weight excess including obesity, and hormonal imbalances like acromegaly and primary hyperparathyroidism.
- Type 2 Diabetes Mellitus
- Obesity without Diabetes
- Acromegaly
- Primary Hyperparathyroidism
- Metabolic Syndrome
Research integrates nutritional strategies with endocrine therapies to improve metabolic health.
Rare Genetic Amyloidosis
Emphasis is placed on hereditary protein‑misfolding diseases affecting the nervous system and heart, notably hereditary transthyretin amyloidosis with polyneuropathy and associated cardiomyopathy.
- Hereditary Transthyretin Amyloidosis with Polyneuropathy
- Transthyretin‑Related Cardiomyopathy
- ATTRv‑PN
- ATTR‑CM
- Amyloid Deposition Disorders
Collaboration with cardiology units supports detailed cardiac phenotype assessment.
Autoimmune & Inflammatory Diseases
Investigation of systemic autoimmunity includes conditions such as primary Sjögren's syndrome, ANCA‑associated vasculitis, and systemic lupus erythematosus.
- Primary Sjögren's Syndrome
- ANCA‑Associated Vasculitis
- Systemic Lupus Erythematosus
- Active Psoriatic Arthritis
- Idiopathic Inflammatory Myopathies
Studies often incorporate biomarker profiling to guide targeted interventions.
Oncology & Solid Tumors
Participation in oncology trials addresses a spectrum of malignancies, including hepatocellular carcinoma, colorectal cancer, and pancreatic adenocarcinoma, as well as biliary and breast cancers.
- Hepatocellular Carcinoma
- Colorectal Cancer
- Pancreatic Ductal Adenocarcinoma
- Advanced Biliary Tract Cancer
- Metastatic Breast Cancer
Multicenter coordination across affiliated hospitals enables comprehensive oncology research.
Cardiovascular & Pulmonary Diseases
Clinical work includes acute coronary events such as acute coronary syndrome, chronic heart failure (heart failure), and chronic lung infections like non‑tuberculous mycobacterial lung infection, together with vascular disorders.
- Acute Coronary Syndrome
- Chronic Heart Failure
- Non‑Tuberculous Mycobacterial Lung Infection
- Pulmonary Hypertension
- Atherosclerotic Cardiovascular Disease
Emphasis is placed on integrating metabolic risk factors with cardiovascular outcomes.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.