Marie L. M.
- Country
- France
- Department
- Dermatology
Research Overview
- Phase 2 Randomized, Double‑Blind, Placebo‑Controlled Dose‑Finding Study of Subcutaneous SAR445399 in Adults with Moderate to Severe Hidradenitis Suppurativa
- Phase 3 Randomized Double-Blind Study of MT-7117 (Dersimelagon Phosphate) in Erythropoietic Protoporphyria and X-Linked Protoporphyria Patients
- Long-term Safety and Tolerability Evaluation of Oral Dersimelagon (MT-7117) in Erythropoietic Protoporphyria and X-Linked Protoporphyria Patients
Data & Insights
Has run more than one trial at 70 of 203 partner sites.
Specializations
Dermatologic inflammatory disease
Clinical research in Dermatology at Centre Hospitalier Universitaire De Nantes includes therapeutic studies in chronic inflammatory and immune-mediated skin disorders, with a strong focus on conditions requiring long-term disease control.
- Atopic dermatitis
- Hidradenitis suppurativa
- Psoriasis
- Vitiligo
- Alopecia areata
The investigator is also involved in studies addressing prurigo nodularis, chronic urticaria, and cutaneous lupus erythematosus.
Autoimmune and vasculitic disorders
Therapeutic interest extends to systemic immune-mediated disease, including cutaneous and multisystem conditions where dermatologic manifestations intersect with broader autoimmune disease management.
- Systemic lupus erythematosus
- Lupus nephritis
- ANCA-associated vasculitis
- Giant cell arteritis
- Systemic sclerosis
Additional activity includes dermatomyositis, pemphigus, mucous membrane pemphigoid, and Behçet’s disease.
Oncodermatology and skin tumors
The investigator contributes to clinical trials in skin cancer and other malignant diseases with cutaneous relevance, supporting therapeutic innovation in both localized and advanced settings.
- Cutaneous squamous cell carcinoma
- Basal cell carcinoma
- Merkel cell carcinoma
- Melanoma
- Cutaneous T-cell lymphoma
Research also covers head and neck squamous cell carcinoma and other advanced solid tumors with dermatologic involvement.
Infectious and perioperative skin-related conditions
Clinical trial involvement includes selected infectious and procedural topics relevant to skin and soft tissue care, with attention to prevention and treatment in hospital-based settings.
- Cutibacterium acnes infection
- Prosthetic joint infection
- Chronic pulmonary aspergillosis
- Herpes simplex virus infection
- Invasive candidiasis
Related work also touches on hospital-acquired infection and postoperative infectious prevention.
Pediatric and rare immune-mediated skin disease
Research activity includes uncommon dermatologic and immune-mediated disorders across age groups, with interest in difficult-to-treat presentations and chronic relapsing disease.
- Hidradenitis suppurativa
- Prurigo nodularis
- Vitiligo
- Erythema multiforme
- Vitiligo
The portfolio also includes mucocutaneous autoimmune disease and severe inflammatory dermatoses.
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