Marie-Dominique T.
- Country
- France
- Department
- Service d'Hématologie et oncologie pédiatrique
Research Overview
- Randomized Phase II/III Study of Cabozantinib Maintenance Versus Best Supportive Care in Osteosarcoma Patients After First‑Line Chemotherapy (FOSTER‑CabOS)
- Phase 2 Multicentre Randomized Trial of Mifamurtide with Post-Operative Chemotherapy in High-Risk Osteosarcoma Patients
- MetroWILMS-1906: Phase 1-2 trial evaluating metronomic chemotherapy in patients with relapsed or refractory Wilms tumor
Data & Insights
Has run more than one trial at 103 of 206 partner sites.
Specializations
Hepatic Oncology
Specializes in the investigation of pediatric liver cancers, with particular focus on hepatoblastoma and hepatocellular carcinoma treatment approaches. The investigator leads research into stratified therapeutic protocols based on risk classification and tumor characteristics.
- Risk-adapted treatment strategies
- Biological sampling studies
- Combined chemotherapy protocols
Bone Cancer Research
Conducts extensive research in high-grade osteosarcoma treatment, investigating innovative therapeutic combinations. The investigator explores both standard chemotherapy protocols and novel approaches including mifamurtide and zoledronic acid interventions.
- Treatment optimization studies
- High-risk patient management
- Metastatic disease protocols
Renal Oncology
Focuses on advanced pediatric renal tumors, particularly Wilms tumor and its treatment modalities. The investigator studies both conventional and metronomic chemotherapy approaches, with special attention to stage IV renal tumors with metastatic presentation.
- Metastatic disease management
- Refractory disease protocols
- Novel therapeutic combinations
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