Marie C.
- Country
- France
- Department
- ONCOLOGY
Research Overview
- Phase III Randomized Trial of Maintenance Olaparib Versus Observation Post-Adjuvant Chemoradiation in p53abn Endometrial Carcinoma
- 2022-501606-35-00 – Randomized, multicenter, open-label, Phase 3 study of mirvetuximab soravtansine in combination with bevacizumab versus bevacizumab alone as maintenance therapy for patients with FRα-high recurrent platinum-sensitive epithelial ovarian, fallopian tube, or primary peritoneal cancers who have not progressed after second-line platinum-based chemotherapy plus bevacizumab (GLORIOSA).
- Randomized Evaluation of Paclitaxel-Carboplatin with Maintenance Niraparib versus Paclitaxel-Carboplatin-Bevacizumab with Maintenance Niraparib-Bevacizumab in Advanced Ovarian Cancer
Data & Insights
Has run more than one trial at 76 of 209 partner sites.
Specializations
Cervical Cancer Research
Specializes in innovative treatments for locally advanced cervical cancer, with particular focus on immunotherapy applications and therapeutic combinations.
- PD-L1 immune checkpoint inhibition
- Chemoradiotherapy integration
- LAG-3 pathway targeting
Active investigation of dual immunotherapy approaches and treatment optimization for early-stage disease management.
Ovarian Cancer Studies
Conducts research in advanced ovarian, fallopian tube, and peritoneal cancers, focusing on maintenance therapy strategies and targeted treatments.
- Combination maintenance therapies
- Folate receptor-targeted treatments
- Platinum-sensitive disease management
Explores novel therapeutic approaches for patients with varying prognostic factors and surgical outcomes.
Endometrial Cancer Expertise
Investigates targeted therapies for advanced and recurrent endometrial cancer, with emphasis on molecular profiling and precision medicine.
- MMR-deficient cancer treatment
- PARP inhibition strategies
- P53-abnormal endometrial cancer
Focuses on developing personalized treatment approaches based on specific molecular characteristics.
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