Marianne K.
- Country
- Denmark
- Department
- Department of Nephrology and Endocrinology
Research Overview
Data & Insights
Has run more than one trial at 0 of 3 partner sites.
Specializations
Nephrology and Renal Immunology
Marianne Klose is involved in clinical research centered on chronic kidney disease, IgA nephropathy, focal segmental glomerulosclerosis, and proteinuria, with additional interest in rapidly progressive glomerulonephritis and acute interstitial nephritis. Her work also extends to kidney-related complications in renal transplantation and end-stage renal disease.
- IgA nephropathy
- Proteinuria
- Chronic kidney disease
- Renal transplantation
Her therapeutic focus includes immune-mediated renal disorders and metabolic complications affecting kidney function.
Endocrine and Metabolic Disorders
Her clinical trial activity includes type 1 diabetes, obesity, overweight, hyperglycaemia after renal transplantation, and endocrine conditions such as congenital adrenal hyperplasia, hypoparathyroidism, and glucocorticoid induced adrenal insufficiency. She is also connected to research in Fabry disease and other inherited metabolic conditions.
- Type 1 diabetes
- Congenital adrenal hyperplasia
- Hypoparathyroidism
- Fabry disease
This area reflects a strong therapeutic interest in chronic endocrine regulation and metabolic disease management.
Cardiovascular Medicine
Her research landscape includes myocardial infarction, heart failure with reduced ejection fraction, atrial fibrillation, cardiogenic shock, aortic stenosis, and atherosclerotic cardiovascular disease. She is also involved in studies addressing pulmonary arterial hypertension, coronary artery bypass grafting, and cardiac arrest.
- Myocardial infarction
- Heart failure
- Pulmonary arterial hypertension
- Cardiac arrest
Her therapeutic interests span acute cardiovascular care, chronic heart disease, and vascular risk reduction.
Autoimmune and Inflammatory Disease
Marianne Klose is active in trials involving myasthenia gravis, systemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis, antineutrophil cytoplasmic antibody-associated vasculitis, antiphospholipid syndrome, and Sjögren's disease. Her portfolio also includes idiopathic inflammatory myopathy, polymyositis, and dermatomyositis.
- Myasthenia gravis
- Systemic lupus erythematosus
- Sjögren's disease
- ANCA-associated vasculitis
Her therapeutic emphasis is directed toward immune dysregulation, antibody-mediated disease, and systemic inflammation.
Oncology and Hematologic Malignancies
Her clinical research also covers a broad oncology portfolio, including acute myeloid leukemia, acute lymphoblastic leukemia, non-Hodgkin lymphoma, multiple myeloma, Hodgkin lymphoma, small cell lung cancer, breast cancer, ovarian cancer, and colorectal cancer. Additional interest is seen in glioblastoma, neuroblastoma, and other solid tumors.
- Acute myeloid leukemia
- Non-Hodgkin lymphoma
- Breast cancer
- Glioblastoma
This research area highlights engagement across both blood cancers and solid tumors, with attention to advanced and treatment-resistant disease.
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