Mariana R.
- Country
- Bulgaria
- Department
- Gastroenterology department
Research Overview
- Phase 3 Evaluation of Pegozafermin Efficacy and Safety in Metabolic Dysfunction-Associated Steatohepatitis with Compensated Cirrhosis
- Evaluation of Efficacy and Safety of VIR-2218 (Elebsiran) and VIR-3434 (Tobevibart) in Chronic Hepatitis D Virus Infection
- Evaluation of Pegozafermin Efficacy and Safety in Patients with Metabolic Dysfunction-Associated Steatohepatitis and Fibrosis: A Phase 3 Clinical Trial
Data & Insights
Has run more than one trial at 71 of 183 partner sites.
Specializations
Viral Hepatitis
The investigator specializes in treating chronic viral hepatitis conditions, with particular focus on hepatitis B virus (HBV) and hepatitis D virus (HDV) infections. Their research encompasses innovative therapeutic approaches for managing these persistent viral infections.
- Chronic HBV management
- HDV infection treatments
- Antiviral therapeutics
Metabolic Liver Disease
The investigator conducts research in metabolic dysfunction-associated steatohepatitis (MASH), focusing on both early-stage disease and advanced complications. Their work includes evaluation of novel treatments for liver fibrosis and cirrhosis associated with metabolic conditions.
- MASH with fibrosis
- Compensated cirrhosis
- Liver histology assessment
Hepatic Complications
The investigator studies advanced liver disease complications, with particular emphasis on hepatic encephalopathy. Their research includes investigation of therapeutic interventions to prevent disease progression and manage complications in patients with cirrhosis.
- Hepatic encephalopathy management
- Cirrhosis-related complications
- Decompensation prevention
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