Mariana-Felicia S.
- Country
- Germany
- Department
- Gynäkologie
Research Overview
Data & Insights
Has run more than one trial at 0 of 37 partner sites.
Specializations
Breast Oncology
Focus on hormone receptor positive HER2 negative breast cancer in advanced and metastatic stages.
- Advanced disease management
- Metastatic progression pathways
- Biomarker-driven patient stratification
Investigations address therapeutic sequencing and disease control.
Endocrine Therapeutics
Evaluation of novel endocrine therapy combinations for hormone‑driven tumors.
- Combination strategies
- Resistance mechanisms
- Hormone signaling modulation
Research targets improved efficacy in patients with prior endocrine exposure.
Targeted Kinase Inhibition
Assessment of CDK4/6 inhibition as a cornerstone for controlling tumor proliferation.
- Cell‑cycle checkpoint targeting
- Synergy with hormonal agents
- Safety profiling in combination regimens
Studies aim to expand therapeutic options for refractory disease.
Digital Health in Oncology
Implementation of digital side effect management platforms to monitor patient-reported outcomes.
- Remote symptom tracking
- Real‑time data integration
- Patient engagement tools
Efforts enhance adherence and early detection of adverse events.
Clinical Outcomes Measurement
Use of progression-free survival as a primary endpoint to evaluate treatment benefit.
- Time‑to‑event analysis
- RECIST‑based disease assessment
- Censoring methodology
Data inform comparative effectiveness across therapeutic cohorts.
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